Results 121 to 130 of about 3,740,437 (360)
The Testing and Treatment of Material for the Construction of Railway Rolling Stock [PDF]
Gordon Jackson
openalex +1 more source
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
High-Pressure Oxygen Test Evaluations [PDF]
The relevance of impact sensitivity testing to the development of the space shuttle main engine is discussed in the light of the special requirements for the engine.
Key, C. F., Schwinghamer, R. J.
core +1 more source
Report of Committee on Standard Tests and Methods of Testing Materials [PDF]
G. C. Henning
openalex +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
The simulation of additive manufacturing processes, such as Wire Arc Additive Manufacturing (WAAM), is becoming increasingly important to predict material and component properties in advance of the real-life manufacturing.
Tim Fritschle+3 more
doaj +1 more source
The Inspection and Testing of Materials Used in the Construction of Locomotives and Rolling Stock [PDF]
T. D. Robson
openalex +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Current activities in standardization of high-temperature, low-cycle-fatigue testing techniques in the United States [PDF]
The American Society for Testing and Materials (ASTM) standard E606-80 is the most often used recommended testing practice for low-cycle-fatigue (LCF) testing in the United States.
Ellis, J. Rodney+2 more
core +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source