Results 121 to 130 of about 2,406,442 (245)

Design & development of a novel house hold compressing device for a wheelie bin [PDF]

open access: yes, 2013
This project consists of researching, designing, developing, prototyping and testing a device that clamps onto a wheelie bin and easily compresses the waste inside.
Burman, Blake, Rehman, Fayyaz
core  

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Polymers for spacecraft hardware - Materials characterization, part I Interim report, Mar. - Dec. 1966 [PDF]

open access: yes
Environmental testing of polymeric materials for spacecraft ...
Cleland, E., Harrington, R., Maxwell, H.
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Development and testing of porous ionizer materials, part I Summary report, Feb. 1965 - May 1966 [PDF]

open access: yes
Development and testing of porous tungsten ionizer materials for cesium contact ...
Butler, K.   +4 more
core   +1 more source

Proceedings of the Symposium on Long-Life Hardware for Space [PDF]

open access: yes, 1970
Two-volume edition of the papers of the symposium is described. It is divided into six sections - parts, materials, management, system testing, component design, and system test.

core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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