Results 131 to 140 of about 4,033,138 (351)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Thickness debit effect of Ni-based single crystal superalloy thin-walled specimens in the VHCF regime based on a vibration fatigue test

open access: yesJournal of Materials Research and Technology
This paper proposes a novel vibration fatigue testing methodology of thin-walled specimens in the very high cycle fatigue (VHCF) regime, with the lifetime up to 109 cycles. A series of novel thin-walled specimens for the single crystal superalloy DD6 are
Wei Xu   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

A thickness debit effect characterization parameter for creep rupture behaviors of nickel-based single crystal superalloys

open access: yesJournal of Materials Research and Technology
Creep rupture tests were conducted on 67 thin-walled DD6 specimens, with thicknesses ranging from 0.35 mm to 1.50 mm, at temperatures of 760 °C, 850 °C, 980 °C, and 1100 °C, revealing a log-linear relationship between rupture lifetimes and specimen ...
Yue Zhang   +5 more
doaj   +1 more source

Polymers for spacecraft hardware - Materials characterization, part I Interim report, Mar. - Dec. 1966 [PDF]

open access: yes
Environmental testing of polymeric materials for spacecraft ...
Cleland, E., Harrington, R., Maxwell, H.
core   +1 more source

Apparatus facilitates high-temperature tensile testing in vacuum [PDF]

open access: yes, 1964
An apparutus for heating refractory materials to high temperatures during tensile testing includes a water-cooled stainless steel vacuum chamber. This contains a resistance heater consisting of a slit tube of tantalum or tungsten to enclose the tensile ...
Sikora, P. F.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Impact perforation testing of stab-resistant armour materials [PDF]

open access: yes, 1995
This paper describes the development of a method for the investigation and comparison of materials for use in stab resistant body armour. A number of polymer composite panels of different thicknesses and construction have been tested.
Angood, C.   +3 more
core  

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