Results 191 to 200 of about 1,805,079 (341)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Empirical validation of size effects in sub-sized tensile specimens for nuclear structural materials. [PDF]

Sci Rep
Li L, Merickel JW, Tang Y, Song R, Rittenhouse JE, Vakanski A, Xu F.   +6 more
europepmc   +1 more source

Thermal Deterioration Test of Electical Insulating Materials using a Mass Spectrograph

, 1958
Yukio Saitō, S. Yamanaka, Taro Hino
openalex   +2 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Mechanical properties and durability of asphalt-concrete composites enhanced with recycled concrete and porcelain aggregates. [PDF]

MethodsX
Hamad WA, Khoshnaw GJ.
europepmc   +1 more source

Material Testing Automation

Journal of the Society of Materials Science, Japan, 1972
Akira Kitamura, Kazuo Kobayashi
openaire   +3 more sources

Chlorella, as a Material of Studying and Testing Phyto-toxicity (Preliminary Report)

, 1958
Yasushi Hashimoto
openalex   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Universal method for contact fatigue determination. [PDF]

MethodsX
Stepankin I, Naizabekov A, Pozdnyakov E, Kuis D, Lezhnev S, Panin Y.   +5 more
europepmc   +1 more source

1054) Pressure Tests of Heavy Grouting Mortar in Prepacked Conctete(Materials. Execution)

, 1959
Yoshio Baba, Isao Chiokai, Toyoshige Sugata, Kazuo Terasawa   +3 more
openalex   +2 more sources