Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Tri-Axial Tests of Metallic Materials at Elevated Temperatures
Masao NISHIHARA+3 more
openalex +2 more sources
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source
Prediction of the packaging chemical migration into food and water by cutting-edge machine learning techniques. [PDF]
Vaferi B+3 more
europepmc +1 more source
SNAP 19 TEST REPORT: THERMAL PERFORMANCE OF MATERIALS AND MECHANICAL JOINTS.
Chun-You Shih
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Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla+4 more
wiley +1 more source
Use of reagent test kits and fentanyl test strips among electronic music festival attendees in Colorado: prevalence, barriers, and behavior in response to drug checking. [PDF]
Piercey CJ+8 more
europepmc +1 more source
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Examination of Stress Corrosion Cracking of Rock Bolts in Simulated Underground Environments. [PDF]
Wu S+4 more
europepmc +1 more source
1004) Exposure Test (3 years) of Asphart-felt and Asphalt-roofing(Materials. Execution)
Ichiro Hatano, Masomori Kato
openalex +2 more sources