Results 51 to 60 of about 30,242 (281)

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Aquaporins in development – a review

Reproductive Biology and Endocrinology, 2005
Water homeostasis during fetal development is of crucial physiologic importance. It depends upon maternal fetal fluid exchange at the placenta and fetal membranes, and some exchange between fetus and amniotic fluid can occur across the skin before full ...
Wintour E Marelyn, Liu Huishu
doaj   +1 more source

Successful Prevention of Fetal Autoimmune-Mediated Heart Block by Combined Therapies With Hydroxychloroquine and Intravenous Immunoglobulin: A Case Report

Frontiers in Cardiovascular Medicine, 2021
A fetal autoimmune-mediated atrioventricular block is a passively acquired autoimmune disease in which maternal autoantibodies enter the fetal circulation via the placenta and subsequently cause inflammation and fibrosis of the atrioventricular node ...
Li Zhao, Yan Zhou, Chuan Wang, Yifei Li, Qi Zhu, Yimin Hua, Lina Qiao, Jinlin Wu, Kaiyu Zhou   +8 more
doaj   +1 more source

High incidence of Y‐chromosome mosaicism in male and female individuals with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy

Epilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an underrecognized pediatric cortical lesion associated with somatic X‐linked SLC35A2 variants in approximately 50% of individuals. The genetic etiology in individuals without detectable SLC35A2 mutations remains undefined, which limits
Erica Cecchini, Till Hartlieb, Ahmed Gaballa, Katja Kobow, Mitali Katoch, Paraskevi Chasani, Georgia Vasileiou, Wiebke Hofer, Lea M. Reisch, Manfred Kudernatsch, Christian G. Bien, Roland Coras, Ingmar Blümcke, Lucas Hoffmann   +13 more
wiley   +1 more source

Separating fetal and maternal placenta circulations using multi-parametric MRI [PDF]

, 2018
Purpose The placenta is a vital organ for the exchange of oxygen, nutrients, and waste products between fetus and mother. The placenta may suffer from several pathologies, which affect this fetal‐maternal exchange, thus the flow properties of the ...
Atkinson, D
core  

The FemTech revolution: Unlocking the potential of new technology for optimizing pregnancy outcomes in low‐ and middle‐income countries and remote areas

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Maternal and neonatal mortality and morbidity rates uncover major global health disparities. Despite ongoing efforts, the rates of maternal and neonatal complications remain substantially higher in low‐ and middle‐income countries (LMICs) compared to high‐income countries (HICs). These high rates are the result of several unmet needs in LMICs,
Nir Melamed, Hema Divakar, Mahesh Choolani, Fionnuala M. McAuliffe, Lin Foo, Hassan Shehata, Gabriel Jones, Vyta Senikas, Eline M. Van der Beek, Nandita Palshetkar, Gabriele Saccone, Vincenzo Berghella, Mauricio A. Cuello, Justin Konje, Bhaskar Bhatt, Augusto Cam, Moses Obimbo, Aris Papageorghiou, Moshe Hod, on behalf of the FIGO Committee on Women's Health and Technology   +19 more
wiley   +1 more source

Maternal nano-titanium dioxide inhalation exposure alters placental cyclooxygenase and oxidant balance in a sexually dimorphic manner

Advances in Redox Research
The placenta plays a critical role in nutrient-waste exchange between the maternal and fetal circulation, and thus impacts fetal growth and development. We have previously shown that nano-titanium dioxide (nano-TiO2) inhalation exposure during gestation ...
Julie A. Griffith, Rachel D. King, Allison C. Dunn, Sara E. Lewis, Brooke A. Maxwell, Timothy R. Nurkiewicz, William T. Goldsmith, Eric E. Kelley, Elizabeth C. Bowdridge   +8 more
doaj   +1 more source

GLP-1 Effects on Maternal Metabolism and Fetal Development [PDF]

, 2022
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that regulates postprandial glucose homeostasis through insulin secretion, food intake, gastric emptying, and suppression of glucagon secretion.
Lu, Cindy V
core  

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim, Cheoljin Park, Donghee Kim, Wonjun Jeong, Jinsoo Lee   +4 more
wiley   +1 more source