Results 51 to 60 of about 65,040 (288)

Aberrant placental structure is corrected with repeated nanoparticle-mediated IGF1 treatments in a Guinea pig model of fetal growth restriction

Translational Research in Anatomy
Background: Fetal growth restriction (FGR) is most commonly due to placental insufficiency. There are currently no treatments for placental insufficiency or FGR, and the only intervention is iatrogenic pre-term delivery. We have previously shown efficacy
Baylea N. Davenport, Rebecca L. Wilson, Alyssa A. Williams, Jaimi A. Gray, Edward L. Stanley, Helen N. Jones   +5 more
doaj   +1 more source

Advances in the Application of Ultrasound for Evaluating Placental Function in Fetal Growth Restriction (FGR) Pregnancy [PDF]

Advanced Ultrasound in Diagnosis and Therapy
Placenta is a vital organ of a unique circulatory system that allows the exchange of nutrients between maternal and fetal circulations, supporting fetal growth during pregnancy.
Shi Ming-Li, Liu Guo-Hui, Bao Fu-Xing
doaj   +1 more source

Exploring maternal-fetal interface with in vitro placental and trophoblastic models

Frontiers in Cell and Developmental Biology, 2023
The placenta, being a temporary organ, plays a crucial role in facilitating the exchange of nutrients and gases between the mother and the fetus during pregnancy. Any abnormalities in the development of this vital organ not only lead to various pregnancy-
Xinlu Liu, Gang Wang, Haiqin Huang, Xin Lv, Yanru Si, Lixia Bai, Guohui Wang, Qinghua Li, Weiwei Yang   +8 more
doaj   +1 more source

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

Compensatory Feto-Placental Upregulation of the Nitric Oxide System during Fetal Growth Restriction [PDF]

, 2012
Background: Fetal Growth Restriction is often associated with a feto-placental vascular dysfunction conceivably involving endothelial cells. Our study aimed to verify this pathogenic role for feto-placental endothelial cells and, coincidentally ...
Begliuomini, Silvia, Boldrini, Antonio, Casarosa, Elena, Coceani, Flavio, Fink, Bruno, Genazzani, Andrea R., Ghirri, Paolo, Pisaneschi, Silvia, Ripoli, Andrea, Sanchez, Angel Matias, Simoncini, Tommaso, Strigini, Francesca A. L.   +11 more
core   +6 more sources

High-elevation adaptation and gestational hypoxia jointly shape vascular development in a rodent placenta. [PDF]

J Physiol
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Wilsterman K, Cheviron ZA, Good JM, Gurnoe-Brantley K, Jewett KE, Kiel K, Larson AM.   +6 more
europepmc   +2 more sources

Uterine natural killer cell heterogeneity: Lessons from mouse models [PDF]

, 2020
Natural killer (NK) cells are the most abundant lymphocytes at the maternal-fetal interface. Epidemiological data implicate NK cells in human pregnancy outcomes.
Sojka, Dorothy K
core   +1 more source

Morphometric analysis of postnatal lung development in the gray short‐tailed opossum (Monodelphis domestica): An ultrastructural study

The Anatomical Record, EarlyView.
Abstract An ultrastructural morphometric analysis of the postnatal development of the lung in the gray short‐tailed opossum (Monodelphis domestica) has been conducted to evaluate the morphofunctional status of this poorly developed marsupial lung immediately following parturition.
Kirsten Ferner
wiley   +1 more source

Successful Prevention of Fetal Autoimmune-Mediated Heart Block by Combined Therapies With Hydroxychloroquine and Intravenous Immunoglobulin: A Case Report

Frontiers in Cardiovascular Medicine, 2021
A fetal autoimmune-mediated atrioventricular block is a passively acquired autoimmune disease in which maternal autoantibodies enter the fetal circulation via the placenta and subsequently cause inflammation and fibrosis of the atrioventricular node ...
Li Zhao, Yan Zhou, Chuan Wang, Yifei Li, Qi Zhu, Yimin Hua, Lina Qiao, Jinlin Wu, Kaiyu Zhou   +8 more
doaj   +1 more source

Placental crises: disruptive selection and maternal under‐investment as the foundations of mammalian placental evolution and dysfunction

Biological Reviews, EarlyView.
ABSTRACT Among the vertebrates, mammals are notable for the dominance of live birth and placental nutrition. The structural diversity of the mammalian placenta is remarkable, despite sharing a single common ancestor and conserved physiological functions.
Davis Laundon, Neil J. Gostling, Ian G. Reddin, Bram G. Sengers, Pascale Chavatte‐Palmer, Rohan M. Lewis   +5 more
wiley   +1 more source