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Advanced maternal age

Obstetrics, Gynaecology & Reproductive Medicine, 2011
Abstract Delayed childbearing is a growing trend in developed countries. Between 1989 and 2009, the number of live births to UK women over 40 almost trebled. This accelerating demographic shift is of major clinical and public health concern, because advanced maternal age has consistently been associated with adverse pregnancy outcomes.
Mills, Tracey A., Lavender, Tina
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Maternal age in trisomy

Annals of Human Genetics, 1988
SummaryBy comparison with a more general theory, data on trisomy in live births, amniocenteses, and spontaneous abortions by year of maternal age are shown to fit a logistic augmented by a proportion independent of maternal age. The frequency of trisomy increases monotonically, with no discrepancy at extremely low or high maternal age.
Newton E. Morton   +3 more
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Decreased maternal age with hydranencephaly

American Journal of Medical Genetics, 1997
We studied parental ages of institutionalized children with hydranencephaly. Mothers under age 20 years and under age 18 years were, respectively, 5 and 10 times as frequent as in the general population, and 3 and 4 times more frequent than for institutionalized control patients.
Mark S. Lubinsky   +2 more
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Maternal Age and Autistic Children

Journal of Developmental & Behavioral Pediatrics, 1984
Maternal age was examined in 52 autistic children. Two matched control groups were also investigated. Both were matched with the autistic group on age, sex, and birth order. In addition, the first control group was matched with the autistic group according to IQ, while the second control group was composed of normally intelligent children and matched ...
Steinhausen, H. C.   +3 more
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Maternal Age and Births in the 1980s

JAMA: The Journal of the American Medical Association, 1982
Projections from the US Bureau of the Census show that as the large "baby boom" cohort ages in the 1980s, the percentage of births to women 35 years or older will increase by 37%, while the percentage of births to teenaged women, the small post-baby-boom cohort, will decrease by 32%. Between 1980 and 1990, for women aged 35 to 44 years, fertility rates
Godfrey P. Oakley   +2 more
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Maternal age and traits in offspring

Nature, 2000
The timing of a mouse's first litter influences the development of her pups. We have investigated the effect of the age at first pregnancy in mice on maternal steroid hormone levels and how these influence the growth and sexual maturation of their pups.
Ming-Hseng Wang, Frederick S. vom Saal
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Alzheimer's Disease and Maternal Age

Journal of the American Geriatrics Society, 1982
Findings from several studies suggest a relationship between Alzheimer's disease and0020Down's syndrome. It has long been known that advanced maternal age is a risk factor for Down's syndrome, and that mothers who give birth to a child with this syndrome have characteristics consistent with accelerated aging.
James B. Leverenz   +5 more
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Maternal age-specific drivers of severe maternal morbidity

American Journal of Obstetrics & Gynecology MFM, 2022
The maternal age influences the risk of adverse pregnancy outcomes, including severe maternal morbidity. However, the leading drivers of severe maternal morbidity may differ between the maternal age groups.To compare the contribution of different risk factors to the risk of severe maternal morbidity between various maternal age groups and estimate ...
Rebecca C. Carr   +3 more
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Maternal Age and Children's Ability

Perceptual and Motor Skills, 1978
Associations of maternal age at birth and subsequent intelligence test scores of children were examined in a series of over 1500 young men from the Netherlands. All subjects were members of 2-child families and were resident in Amsterdam at age 19 yr.
Zena Stein   +2 more
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Maternal Age and Parental Loss

British Journal of Psychiatry, 1968
Maternal age at parturition, birth order, and parental loss have all been extensively investigated as possible causal or concomitant factors in a wide variety of mental disorders. Thus, to take an extreme example, the influence of maternal age on one of the two main kinds of mongolism is well known and can hardly have other than a biological ...
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