Results 61 to 70 of about 788,578 (302)

Prenatal chromosomal microarray analysis in a large Chinese cohort of fetuses with congenital heart defects: a single center study

Orphanet Journal of Rare Diseases
Background and objectives Congenital heart defect (CHD) is one of the most common birth defects. The aim of this cohort study was to evaluate the prevalence of chromosomal abnormalities and the clinical utility of chromosomal microarray analysis (CMA) in
Qing Lu, Laipeng Luo, Baitao Zeng, Haiyan Luo, Xianjin Wang, Lijuan Qiu, Yan Yang, Chuanxin Feng, Jihui Zhou, Yanling Hu, Tingting Huang, Pengpeng Ma, Ting Huang, Kang Xie, Huizhen Yuan, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu   +18 more
doaj   +1 more source

Are Maternal and Child Care Programs Reaching the Poorest Regions in the Philippines? [PDF]

, 2008
While the national average for maternal and child health services utilization shows improvement, the Philippines is yet to achieve the MDG targets for maternal and child health.
Lagrada, Leizel P., Lavado, Rouselle F.
core  

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Vitamin K2 deficiency associated with short stature in children: a cross-sectional study

BMC Pediatrics
Background Short stature in children is a common concern that can result from various underlying conditions. While factors such as growth hormone deficiency and nutritional deficiencies are well-known contributors, the role of vitamin K2 (VK2) in the ...
Yanjie Shen, Geyong Shi, Shumei Wen, Wei Luo, Ke Wang   +4 more
doaj   +1 more source

Reusable period products: use and perceptions among young people in Victoria, Australia

BMC Women's Health, 2023
Background Reusable menstrual products have expanded the choices available for menstrual care and can offer long-term cost and environmental benefits.
Caitlin Ramsay, Julie Hennegan, Caitlin H. Douglass, Sarah Eddy, Alexandra Head, Megan S. C. Lim   +5 more
doaj   +1 more source

Early risk factors for adolescent antisocial behaviour: an Australian longitudinal study [PDF]

, 2004
Objective: This investigation utilizes data from an Australian longitudinal study to identify early risk factors for adolescent antisocial behaviour.
Achenbach T M, Achenbach T M, Australian Bureau of Statistics, Bracken B A, Cravioto J, Dunn L M, Farrington D P, Huesmann L R, Kazdin A, Lipsey M W, Malmgren K W, Menard S, Moffitt T E, Mukherjee S, National Crime Prevention, Prior M, Rutter M, Sanders M R, Silburn S R, van Kesteren J, Wasserman G A   +20 more
core   +2 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Genetic and immunologic findings in children with recurrent aphthous stomatitis with systemic inflammation

Pediatric Rheumatology Online Journal, 2021
Background Recurrent aphthous stomatitis with systemic signs of inflammation can be encountered in inflammatory bowel disease, Behçet’s disease (BD), Systemic Lupus Erythematosus (SLE).
Martina Girardelli, Erica Valencic, Valentina Moressa, Roberta Margagliotta, Alessandra Tesser, Serena Pastore, Ottavia Spadola, Emmanouil Athanasakis, Giovanni Maria Severini, Andrea Taddio, Alberto Tommasini   +10 more
doaj   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Fetal deaths from birth defects in Hunan Province, China, 2016–2020

Scientific Reports
To describe the fetal death rate of birth defects (including a broad range of specific defects) and to explore the relationship between fetal deaths from birth defects and a broad range of demographic characteristics.
Xu Zhou, Jian He, Aihua Wang, XinJun Hua, Ting Li, Qin Liu, Junqun Fang, Yurong Jiang, Yingrui Shi   +8 more
doaj   +1 more source