Results 41 to 50 of about 34,680 (249)

The Relationship Between Parental Psychological Control and College Students’ Non-Suicidal Self-Injury: The Chain Mediation Roles of Relative Deprivation and Depression and the Moderating Role of Peer Relationships

Behavioral Sciences
Previous research has demonstrated that parental psychological control increases the likelihood of non-suicidal self-injury (NSSI) among college students. However, the underlying mechanisms of this association remain unclear.
Sachula Cui, Qiang Bao
doaj   +1 more source

Neonatal stress-induced affective changes in adolescent Wistar rats: early signs of schizophrenia-like behavior

Frontiers in Behavioral Neuroscience, 2014
Psychiatric disorders are multifactorial diseases with etiology that may involve genetic factors, early life environment and stressful life events. The neurodevelopmental hypothesis of schizophrenia is based on a wealth of data on increased vulnerability
Carlos Eduardo Neves Girardi, Natália Cristina Zanta, Deborah eSuchecki   +2 more
doaj   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Maternal Separation and the Risk of Drug Abuse in Later Life [PDF]

Addiction and Health, 2016
Maternal separation (MS) is defined as the termination of the continuity of mother-child relationship after the relationship is established. Although MS and maternal deprivation are different in terms of their definitions, these two terms are usually ...
Fatemeh Delavari, Vahid Sheibani, Saeed Esmaeili-Mahani, Nouzar Nakhaee   +3 more
doaj  

The impact of the mother on the hypothalamic-pituit aryadrenal, hypothalamic-pituit ary-gonadal and somatotropic axes activity of offspring during postnatal ontogeny

Acta Biologica, 2015
During the rearing period, most of the physiological processes of offspring are under maternal regulation, which overcomes the influence of external environmental factors.
Natalia Chmielewska, Marta Wańkowska
doaj   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Area-level deprivation and preterm birth: results from a national, commercially-insured population

BMC Public Health, 2019
Background Area-level deprivation is associated with multiple adverse birth outcomes. Few studies have examined the mediating pathways through which area-level deprivation affects these outcomes.
Renee Mehra, Fatma M. Shebl, Shayna D. Cunningham, Urania Magriples, Eric Barrette, Carolina Herrera, Katy B. Kozhimannil, Jeannette R. Ickovics   +7 more
doaj   +1 more source

Is maternal deprivation the root of all evil?

Avances en Psicología Latinoamericana, 2008
In this paper we seriously entertain the question, “Is maternal deprivation the root of all evil?” Our consideration of this question is broken down into three parts.
Karyn B. Purvis, David R. Cross
doaj  

The quantification and epistemology of medicines use and polypharmacy tested in an observational study

British Journal of Clinical Pharmacology, EarlyView.
Definitions of ‘medicines use’ and ‘polypharmacy’ may refer to all medicines, regular long‐term medicines or another subset. Valid definitions of medicines use should incorporate type of use (long term, short course and as needed [PRN]), changes in use (start, stop and dose change) and a description of temporal examination (cross‐sectional or ...
Lorna Pairman, Paul Chin, Matthew Doogue
wiley   +1 more source