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Early Life Stress, Mood, and Anxiety Disorders [PDF]
Chronic Stress, 2017 Early life stress has been shown to exert profound short- and long-term effects on human physiology both in the central nervous system and peripherally. Early life stress has demonstrated clear association with many psychiatric disorders including major ...
Shariful A. Syed, Charles B. Nemeroff
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Early life stress, HPA axis adaptation and mechanisms contributing to later health outcomes
Frontiers in Endocrinology, 2014 Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, which then modulates the degree of adaptation and response to a later stressor. It is known that early life stress can impact on later health but less is known about how early life stress ...
Jayanthi eManiam +2 more
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Early life stress impairs hippocampal subfield myelination [PDF]
Communications BiologyThe hippocampus is an archicortical structure that is highly sensitive to experience and is made up of individual subfields. These subfields, crucial for learning and memory, rapidly develop and are vulnerable to early stress, yet the mechanisms are ...
Emily S. Nichols +5 more
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Persistent open chromatin state in early-life stress-activated cells of the VTA [PDF]
Scientific ReportsEarly-life stress sensitizes individuals to subsequent stressors to increase lifetime risk for psychiatric disorders. Within the ventral tegmental area (VTA), a mesolimbic brain region implicated in stress response and mental health, early-life stress ...
Rebekah L. Rashford +4 more
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Neuropsychiatric Disease and Treatment, 2008 Robert Paul1, Lorrie Henry2, Stuart M Grieve3, Thomas J Guilmette2,4, Raymond Niaura4, Richard Bryant5, Steven Bruce1, Leanne M Williams3,6, Clark C Richard7, Ronald A Cohen4, Evian Gordon3,71University of Missouri, St. Louis, St.
Robert Paul +5 more
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Examining Social Touch in Early-Life Stress [PDF]
BJPsych OpenAims Social contact is crucial for both immediate and later development of adaptive social and emotional behaviour. Tactile experiences during childhood influence the development of the social brain and frequent affectionate touch is associated with ...
Lena Lim
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Early-life stress sensitizes response to future stress: Evidence and mechanisms [PDF]
Neurobiology of StressEarly-life stress sensitizes individuals to additional stressors and increases lifetime risk for mood and anxiety disorders. Research in both human populations and rodent models of early-life stress have sought to determine how different types of ...
Catherine Jensen Peña
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Alteration of somatosensory response in adulthood by early life stress.
Frontiers in Molecular Neuroscience, 2015 Early-life stress is well known as a critical risk factor for mental and cognitive disorders in adulthood. Such disorders are accompanied by altered neuro- (synapto-) genesis and gene expression.
Yusuke eTakatsuru, Noriyuki eKoibuchi
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Journal of Mazandaran University of Medical Sciences, 2020 Background and purpose: Stressful events in early-life induce metabolic disorders in adolescence. The aim of this study was to investigate the effect of early-life stress on number or area of Langerhans islets in exposure to foot-shock and psychological ...
Homeira Zardooz +2 more
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Early Life Stress and Gut Microbiome Dysbiosis: A Narrative Review
StressesBackground: Exposure to early life stress significantly increases the risk of psychopathology later in life. However, the impact of early life stress on the gut microbiome and its potential role in mental health outcomes remains insufficiently understood.
Alejandro Borrego-Ruiz, Juan J. Borrego
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