Results 31 to 40 of about 13,943,232 (281)

Effect of Early Life Stress on the Epigenetic Profiles in Depression

Frontiers in Cell and Developmental Biology, 2020
Depression is one of the most common mental disorders and has caused an overwhelming burden on world health. Abundant studies have suggested that early life stress may grant depressive-like phenotypes in adults. Childhood adversities that occurred in the
Ming Li, Xiying Fu, Wei Xie, Wanxu Guo, Bingjin Li, Ranji Cui, Wei Yang   +6 more
doaj   +1 more source

Perceived control, loneliness, early-life stress, and parents’ perceptions of stress

Scientific Reports, 2023
The COVID-19 pandemic has highlighted the importance of understanding what contributes to individual variability in experiences of stress. Increases in stress related to the pandemic have been especially pronounced in parents, indicating a need for ...
Karen E. Smith, Eileen Graf, Kelly E. Faig, Stephanie J. Dimitroff, Frederica Rockwood, Marc W. Hernandez, Greg J. Norman   +6 more
doaj   +1 more source

Early life stress, HPA axis adaptation and mechanisms contributing to later health outcomes

Frontiers in Endocrinology, 2014
Stress activates the hypothalamic-pituitary-adrenal (HPA) axis, which then modulates the degree of adaptation and response to a later stressor. It is known that early life stress can impact on later health but less is known about how early life stress ...
Jayanthi eManiam, Christopher eAntoniadis, Margaret eMorris   +2 more
doaj   +1 more source

Early Life Stress: Nature and Nurture [PDF]

Endocrinology, 2014
Recent and still nascent understanding of epigenetic marks, how they occur and are modified, has been an enormous boon to studies in the fields of endocrinology and neuroscience. Because the genetic DNA sequence does not usually change during the lifetime of the individual, it had been difficult to understand how marked and persistent changes in gene ...
openaire   +4 more sources

Early life stress concept: introduction

European Journal of Psychotraumatology, 2012
Rationale/statement of the problem : Stressful experiences during early life can remodel brain circuitry underlying behavioral adaptation with consequences for resilience and vulnerability to emotional and cognitive disorders. At least in the rodent this
E. Ronald de Kloet, Nikolaos P. Daskalakis   +1 more
doaj   +1 more source

Psychosocial stress experience and DNA methylation in humans - implications for stress-adaptation and -resilience [PDF]

, 2014
: Background: Psychosocial stress, especially early in life, is a risk factor for mental disorders. Recent evidence suggests that stress-related changes in epigenetic patterns, including DNA methylation, could mediate this association. Aim: to examine a
Unternaehrer, Eva
core   +1 more source

Reward-related neural correlates of early life stress in school-aged children

Developmental Cognitive Neuroscience, 2021
Objectives: Early life stress likely contributes to dysfunction in neural reward processing systems. However, studies to date have focused almost exclusively on adolescents and adults, measured early life stress retrospectively, and have often failed to ...
Nicholas M. Morelli, Michael T. Liuzzi, Jacqueline B. Duong, Maria Kryza-Lacombe, Emma Chad-Friedman, Miguel T. Villodas, Lea R. Dougherty, Jillian Lee Wiggins   +7 more
doaj   +1 more source

Early Life Stress, Hormones, and Neurodevelopmental Disorders

Hormone Research in Paediatrics, 2022
Background: Early life stress (ELS) describes a broad spectrum of adverse and stressful prenatal events, namely, prenatal maternal stress (PMS), or early postnatal events, which can have detrimental long-term influences on the physiology, cognition, and behavior of an individual. There is abundant evidence indicating that ELS exerts its lasting effects
Gerasimos Makris, Anna Eleftheriades, Panagiota Pervanidou   +2 more
openaire   +3 more sources

Early-life manipulation of cortisol and its receptor alters stress axis programming and social competence [PDF]

, 2019
In many vertebrate species, early social experience generates long-term effects on later life social behaviour. These effects are accompanied by persistent modifications in the expression of genes implicated in the stress axis.
Reyes-Contreras, Maria, Reyes Contreras, Maria, Taborsky, Barbara, Rennison, Diana J., Glauser, Gaétan, Rennison, Diana J   +5 more
core   +2 more sources

Stressors, Appraisal of Stressors, Experienced Stress and Cardiac Response:A Real-Time, Real-Life Investigation of Work Stress in Nurses [PDF]

, 2015
Background: Stress in health care professionals may reflect both the work and appraisal of work and impacts on the individuals, their patients, colleagues and managers.Purpose: The purpose of the present study is to examine physiological and ...
Farquharson, B., Julia Allan, Marie Johnston, Martyn Jones (720171), Bell, Cheryl, Jones, Martyn C, Martyn Jones, Ian Ricketts (16669965), Marie Johnston (18271), Farquharson, Barbara, Derek Johnston, Johnston, D., Barbara Farquharson (16669962), Derek Johnston (3064002), Bell, C., Jones, M., Patricia Schofield, Jones, Martyn, Barbara Farquharson, Ricketts, I., Schofield, Patricia, Patricia Schofield (625809), Johnston, M., Cheryl Bell (16669959), Bell, Cheryl Louise, Cheryl Bell, Ian Ricketts, Johnston, Derek, Julia Allan (4991684), Allan, J., Allan, Julia, Johnston, Marie, Johnston, Derek W, Ricketts, Ian, Allan, Julia L   +34 more
core   +1 more source