Results 51 to 60 of about 920,236 (292)

Tough adults, frail babies: an analysis of stress sensitivity across early life-history stages of widely introduced marine invertebrates

, 2012
All ontogenetic stages of a life cycle are exposed to environmental conditions so that population persistence depends on the performance of both adults and offspring.
Rius Viladomiu, Marc, Turon Barrera, Xavier, Turon Xavier, Ordóñez Sánchez, Víctor, Christopher D McQuaid, McQuaid, Christopher D., M Carmen Pineda, Pineda M. Carmen, Ordóñez Víctor, McQuaid, C.D., Ordóñez, Víctor, Turon, Xavier, Rius Marc, Susanna López-Legentil, López Legentil, Susanna, Marc Rius, López-Legentil, Susanna, Pineda, M. Carmen, López-Legentil Susanna, Rius, Marc, McQuaid Christopher D., Pineda Torres, Mari Carmen, López-Legentil, S., Xavier Turon, Pineda, M. C., Víctor Ordóñez   +25 more
core   +1 more source

Differential effects of two early life stress paradigms on cerebellar-dependent delay eyeblink conditioning

, 2020
Early life stress paradigms have become prominent in the animal literature to model atypical development. Currently, two models have prevailed within the literature: (1) limited bedding or nesting and (2) maternal separation or deprivation.
Hetrick, William P., Moussa-Tooks, Alexandra B., Green, John T.   +2 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Early life stress and development: potential mechanisms for adverse outcomes

Journal of Neurodevelopmental Disorders, 2020
Background Chronic and/or extreme stress in early life, often referred to as early adversity, childhood trauma, or early life stress, has been associated with a wide range of adverse effects on development.
Karen E. Smith, Seth D. Pollak
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact of Early Life Stress on Reward Circuit Function and Regulation

Frontiers in Psychiatry, 2021
Early life stress – including experience of child maltreatment, neglect, separation from or loss of a parent, and other forms of adversity – increases lifetime risk of mood, anxiety, and substance use disorders.
Jamie L. Hanson, Alexia V. Williams, Debra A. Bangasser, Catherine J. Peña   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Impact of Early Life Stress on Neurobiological Vulnerability to Obsessive-Compulsive Disorder: Early Life Stress & Neurobiological OCD Risk

Brain Science Advances
The impact of early life stress on neurobiological vulnerability to obsessive-compulsive disorder (OCD) is a major focus of psychiatric research. Individuals with OCD frequently report that psychosocial stress exacerbates their symptoms, with many ...
Akshita Debnath, Souhrid Sarkar
doaj   +1 more source