Results 41 to 50 of about 443,472 (266)
eLifeLoss of maternal SETDB1, a histone H3K9 methyltransferase, leads to developmental arrest prior to implantation, with very few mouse embryos advancing beyond the eight-cell stage, which is currently unexplained. We genetically investigate SETDB1’s role in
Tie-Bo Zeng +5 more
doaj +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Animals, 2023 The goal of this study was to estimate (co) variance components and genetic parameters for pre- and post-weaning growth traits in Dağlıç sheep, considering the direct additive genetic, maternal genetic, and maternal permanent environmental effects, with ...
Serdar Koçak +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
WEIGHT VARIATIONS IN NEWBORN DOMESTIC PIGS AND THE ADAPTATION PROCESS
Вавиловский журнал генетики и селекции, 2015 This article shows that weight dynamics in newborn domestic pig individuals reflects adaptive changes in the gene pool of the population. Our results show that the coordination of the gene pool with altered ambient conditions in domestic pigs may be long.
S. V. Nikitin +2 more
doaj
Ecology and EvolutionAdmixture between crops and their wild relatives may lead to the evolution of aggressive weeds in agricultural and natural habitat. As many crops and their wild relatives belong to the same species, admixture is common, and the low fitness of crop‐wild ...
Ignacio J. Fanna +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Estimation models of variance components for farrowing interval in swine
Brazilian Archives of Biology and Technology, 2009 The main objective of this study was to evaluate the importance of including maternal genetic, common litter environmental and permanent environmental effects in estimation models of variance components for the farrowing interval trait in swine.
Aderbal Cavalcante Neto +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Zfp57 Exerts Maternal and Sexually Dimorphic Effects on Genomic Imprinting
Frontiers in Cell and Developmental Biology, 2022 Zfp57 has both maternal and zygotic functions in mouse. It maintains genomic imprinting at most known imprinted regions and controls allelic expression of the target imprinted genes in mouse embryos. The DNA methylation imprint at many imprinting control
Zhen Xu +12 more
doaj +1 more source