Results 31 to 40 of about 443,472 (266)
Maternal Prepregnancy 5-Hydroxytryptamine Exposure Affects the Early Development of the Fetus
In recent decades, the increasing incidence of depression has contributed to an increase in the use of serotonergic drugs, such as antidepressants, which predisposes humans to serotonin syndrome.
Yu Han +12 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
ObjectivePrior studies have shown that there is an inverse association between birth weight and stroke in adulthood; however, whether such association is causal remains yet known and those studies cannot distinguish between the direct fetal effect and ...
Ting Wang +10 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Problems in estimating maternal effects [PDF]
Abstract The basic problems inherent in the estimation of maternal effects are considered. A maternal effect is defined as an effect contributed to the phenotypic value of an offspring by his dam. The two most important problems are the confounding of the maternal effect of the dam and her genetic contribution to the genotypic value of her offspring ...
Schlote W, Nitter G
openaire +8 more sources
This study was conducted at Green House IPB Cikabbayan Darmaga Research Station. Soybean tolerance genotype (Ceneng) was crossed with sensitive genotype (Godek A) to study the mode of inheritance in tolerance to shade.
Titin Handayani
doaj +1 more source
Heterosis in the second and third generation affects litter size in a crossbreed mink (Neovison vison) population [PDF]
Litter sizes in a cross between Brown and Black mink color types were observed through six generations. Litter size was significantly affected by yearly environmental variations.
Thirstrup Janne +3 more
doaj +1 more source
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source

