Results 91 to 100 of about 3,104,714 (298)

An Injectable, Self‐Expanding Hemostatic Foam for Field‐Compatible Postpartum Hemorrhage Management

Advanced Science, EarlyView.
Postpartum hemorrhage is the leading cause of maternal death worldwide, yet many treatments are hard to use outside well‐equipped hospitals. This work introduces an easy‐to‐use device that rapidly delivers a degradable foam into the uterus. The foam stops bleeding through pressure and clotting support, offering a practical option for low‐resource ...
Charlotte Meyer, Noël Strasser, Ilakkiya Ravindrarajah, Elsa Wrenger, Kristian Ivkovic, Jan Ševčík, Sima Šarčević, Lenka Červenková, Jáchym Rosendorf, Václav Liška, Alexandre H. Anthis, Thomas Rduch, Inge K. Herrmann   +12 more
wiley   +1 more source

Birmingham Maternity Hospital. [PDF]

BJOG: An International Journal of Obstetrics & Gynaecology, 1908
n ...
openaire   +2 more sources

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Complex chromosomal rearrangements induce embryonic chromosomal imbalance and significantly compromise reproductive outcomes

Contraception and Reproductive Medicine
This study evaluated Preimplantation Genetic Testing for Structural Rearrangements (PGT‑SR) outcomes in carriers of complex chromosomal rearrangements (CCRs).
Yueyun Lan, Xihe Deng, Sheng He, Jingsi Luo, Jiasun Su, Wei Li, Chaofan Zhou, Xianglian Tang, Yuan Wei, Minpan Huang, Jingrong Luo, Jinhui Shu, Caizhu Wang, Xin Zhao, Hong Zhou, Peng Huang   +15 more
doaj   +1 more source

Identification of EVC variants and the preimplantation genetic testing in a Chinese family

Frontiers in Medicine
Fetal genetic skeletal disorders are common congenital anomalies with notable genetic and phenotypic heterogeneity. Genetic analysis plays an important role in the definitive diagnosis of these skeletal conditions.
Haiyan Luo, Zhen Guo, Yao Yu, Jia Chen, Qing Lu, Yan Yang, Ting Huang, Danping Liu, Wangli Nie, Wan Lu, Bicheng Yang, Jun Zou, Yanqiu Liu, Yongyi Zou   +13 more
doaj   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

Modbury Hospital aerial photos

Three photos showing Modbury Hospital from an aerial angle on the same sheet of ...
Modbury Hospital
core   +1 more source

Modbury Hospital Cashier photo

Large Colour photo of a man talking to the cashier in the Modbury Hospital ...
Modbury Hospital
core   +1 more source

Application of family whole-exome sequencing for prenatal diagnosis—an analysis of 357 cases

Frontiers in Medicine
ObjectiveTranslation of fertility risks through whole-exome sequencing of family lines to identify variants that explain patient’s clinical phenotypes.Methods1.
Yijun Ge, Huizhen Yuan, Yao Yu, Junfang Xiao, Danping Liu, Yongbao Peng, Ying Liu, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu   +10 more
doaj   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source