Results 71 to 80 of about 3,104,714 (298)

HPV genotype distribution and cervical lesion severity in HPV-positive women: a study from the Guizhou Province cervical cancer screening program

open access: yesVirology Journal
Objective To analyze the infection status and subtype distribution of high-risk human papillomavirus (hrHPV) and their relationship with cervical lesions among women undergoing cervical cancer screening in Guizhou Province, thereby informing HPV vaccine ...
Xingjing Luo   +7 more
doaj   +1 more source

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

open access: yesAdvanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li   +8 more
wiley   +1 more source

Modbury Hospital Room photos

open access: yes, 1999
Colour photos of rooms in Modbury Hospital before any tables or equipment was in ...
Modbury Hospital
core   +1 more source

Modbury Hospital Kiosk photo

open access: yes, 1982
Black and white photo of two staff members sitting down and having coffee in the Modbury Hospital ...
Modbury Hospital
core   +1 more source

Correlation between intestinal flora and glucuronidase indexes and sex hormone levels and their diagnostic efficacy evaluation for premature ovarian failure

open access: yesBMC Women's Health
Background Premature ovarian failure (POF), affecting women under 40, is characterized by early loss of ovarian function with unclear pathogenesis.
Yun Zhang   +6 more
doaj   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

open access: yesAdvanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou   +6 more
wiley   +1 more source

Analysis of human papillomavirus infection and its correlation with cervical lesions in Huizhou women

open access: yesScientific Reports
To analyze the genotype distribution of human papillomavirus (HPV) infection in women in the Huizhou region of China and determine its correlation with age and degree of cervical lesions, with the aim to understand the characteristics of HPV infection in
Xiaoting Wang   +5 more
doaj   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

open access: yesAdvanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee   +11 more
wiley   +1 more source

Modbury Hospital Foundation brochure

open access: yes
Brochure for the Modbury Hospital ...
Modbury Hospital
core   +1 more source

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