Results 71 to 80 of about 3,902,811 (261)

The impact of fertility changes on maternal mortality [PDF]

As less developed countries experience lower fertility, the age/parity distribution of pregnancies may shift. While these shifts may affect maternal mortality levels, their exact impact remains largely unknown. The aim of this thesis is to quantify the
Huang, Wei
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Early Maternal Employment and Family Wellbeing [PDF]

This study uses longitudinal data from the NICHD Study on Early Child Care (SECC) to examine the effects of maternal employment on family well-being, measured by maternal mental and overall health, parenting stress, and parenting quality.
Sara Markowitz, Pinka Chatterji, Jeanne Brooks-Gunn   +2 more
core  

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

Maternal Employment and Adolescent Development [PDF]

This study investigates how maternal employment is related to the outcomes of 10 and 11 year olds after controlling for a wide variety of child, mother and family background characteristics.
Christopher J. Ruhm
core  

Predictors of maternal psychological distress in rural India: a cross-sectional community-based study. [PDF]

, 2012
Maternal common mental disorders are prevalent in low-resource settings and have far-reaching consequences for maternal and child health. We assessed the prevalence and predictors of psychological distress as a proxy for common mental disorders among ...
Nair, Nirmala, Rath, Suchitra, Gope, RK, Copas, Andrew, Prost, Audrey, Mahapatra, R, Prost, A, Tripathy, P, Bajpai, Aparna, Costello, A, Lakshminarayana, Rashmi, Rath, S, Mahapatra, Rajendra, Costello, Anthony, Tripathy, Prasanta, Bajpai, A, Gope, Raj Kumar, Rath, Shibanand, Patel, V, Patel, Vikram, Lakshminarayana, R, Nair, N, Copas, A   +22 more
core   +1 more source

Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform Toward Non‐Invasive Diagnostics

Advanced Science, EarlyView.
Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform toward Non‐Invasive Diagnostics is a nature‐inspired strategy that engineers controlled randomness within block copolymer lamellae to achieve optical isotropy without compromising nanoscale periodicity.
Jin Man Kim, Wonsik Kim, Wansun Kim, Yeon‐Hee Kim, Samjin Choi, Jang Hwan Kim, Hyeong Min Jin   +6 more
wiley   +1 more source

The Relation between Treated Maternal Urinary Tract Infection and Adverse Maternal, Prenatal Outcomes in Pregnant Women of Ardabil, Iran [PDF]

Background and Objective: ­ Urinary tract infection is one of the most common bacterial infections during pregnancy and has also been implicated as a risk factor for adverse maternal and prenatal ­­outcomes.
مرادی, شهلا, نخستین, بابک, حضرتی, صادق, سلیمی, سوسن, طهماسبی, پریسا, عالی جهان, راحله   +5 more
core  

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source