Results 91 to 100 of about 3,902,811 (261)

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Knowledge Summary 27: Death reviews: maternal, perinatal and child

Many maternal, perinatal and child deaths are preventable and progress towards Millennium Development Goals 4&5, to reduce child mortality and improve maternal health, has been insufficient in many parts of the world.
Partnership for Maternal, Newborn and Child Health, Theiss-Nyland, K, Rechel, B   +2 more
core   +1 more source

Association between maternal serum homocysteine concentrations in early pregnancy and adverse pregnancy outcomes

, 2020
Background: There is still conflicting evidence on the extent to which maternal hyperhomocysteinemia is a risk factor for pregnancy complications. Aims: The study aimed to investigate the impact of elevated maternal homocysteine concentrations on adverse
Nwogu, C., Sekumade, A., John-Olabode, S., Okunade, K., Adenekan, M., Oluwole, A.   +5 more
core   +1 more source

Preconception care for diabetic women for improving maternal and fetal outcomes : a systematic review and meta-analysis [PDF]

, 2010
Background Preexisting diabetes mellitus is associated with increased risk for maternal and fetal adverse outcomes. Despite improvement in the access and quality of antenatal care recent population based studies demonstrating increased congenital ...
Ghada A Bawazeer, Alansari, Lubna A., Rasmeia A Alzeidan, Samia A Esmaeil, Wahabi, Haifa A. A., Lubna A Alansari, Wahabi, Hayfaa A., Alzeidan, Rasmeia A., Alzeidan, Rasmieh A., Hayfaa A Wahabi, Bawazeer, Ghada A., Esmaeil, Samia A.   +11 more
core   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

How Sibling Composition Affects Adolescent Schooling Outcomes When Welfare Reform Policies Increase Maternal Employment [PDF]

Pooling across seven experimental studies, this paper examines the role of sibling composition in influencing the effects of 14 welfare and employment programs on adolescents.
Lisa A. Gennetian
core  

Impact of user fees on maternal health service utilization and related health outcomes: a systematic review.

, 2013
OBJECTIVE: To assess the evidence of the impact of user fees on maternal health service utilization and related health outcomes in low- and middle-income countries, as well as their impact on inequalities in these outcomes.
Campbell, OM, Campbell, Oona MR, Dzakpasu, Susie, Dzakpasu, S, Powell-Jackson, T, Powell-Jackson, Timothy   +5 more
core   +1 more source

Maternal aflatoxin exposure during pregnancy and adverse birth outcomes in Uganda [PDF]

, 2018
Aflatoxins are toxic metabolites of Aspergillus moulds and are widespread in the food supply, particularly in low- and middle-income countries.
Griffiths, Jeffrey K., Webb, Patrick, Nshakira, Nathan, Ausman, Lynne M., Xue, Kathy S., Lauer, Jacqueline M., Agaba, Edgar, Ghosh, Shibani, Duggan, Christopher P., Wang, Jia-Sheng   +9 more
core   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at referral hospitals of amhara regional state, institutional-based cross-sectional study, North-West Ethiopia

Frontiers in Global Women's Health
IntroductionSevere preeclampsia/eclampsia is a multi-systemic pregnancy condition that manifests after 20 weeks of gestation and is linked to a high global rate of maternal morbidity and mortality.
Misganaw Fikrie Melesse, Getie Lake Aynalem, Martha Berta Badi, Bewket Yeserah Aynalem   +3 more
doaj   +1 more source