Results 111 to 120 of about 788,741 (309)

Juvenile rank acquisition is associated with fitness independent of adult rank [PDF]

, 2020
Social rank is a significant determinant of fitness in a variety of species. The importance of social rank suggests that the process by which juveniles come to establish their position in the social hierarchy is a critical component of development. Here,
Holekamp, Kay E., Shizuka, Daizaburo, Strauss, Eli D.   +2 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Evaluating Clinical Outcomes in Pregnant Women with Severe Mental Illness: A Retrospective Audit at University Hospitals Birmingham

Wah Academia Journal of Health and Nutrition
Background: Severe mental illness (SMI) is a leading preventable cause of maternal death in the postpartum period with suicide and psychiatric illness contributing to over one third of deaths between 6 weeks and one year postpartum.
Asia Khan
doaj   +1 more source

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

Pregnancy Outcomes in Women with Crohn’s Disease: A Literature Review

Journal of Education, Health and Sport
Background Crohn’s disease (CD) is a chronic inflammatory bowel disease commonly diagnosed in women of reproductive age. While treatments have improved over the years, pregnancy in women with CD still presents certain challenges. Recent findings suggest
Maria Teper, Natalia Marianna Kubiś, Wiktor Perz , Anhelina Korolchuk , Aleksander Polus , Bartosz Palacz , Julia Anna Wrona, Anna Gluzicka , Liwia Olczyk , Jędrzej Piotrowski   +9 more
doaj   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

The effect of late-gestational anemia on maternal and neonatal outcomes in twin pregnancies: a retrospective cohort study

Annals of Medicine
Background Due to their unique physiology, twin pregnancies face complex anemia-related risks. While anemia’s impact is documented in singleton pregnancies, evidence in twins remains scarce.
Xiayang Li, Yishuai Huang, Jie Chen, Xu Cao, Yu Zhang, Yiting Li, Kangxin Wang, Fuyang Zhao, Siyi Ren, Shaoli Wang, Pengfei Qu   +10 more
doaj   +1 more source

A multicountry randomized controlled trial of comprehensive maternal nutrition supplementation initiated before conception: the Women First trial. [PDF]

, 2019
Background: Reported benefits of maternal nutrition supplements commenced during pregnancy in low-resource populations have typically been quite limited.
Ali, Sumera A., Bauserman, Melissa, Bose, Carl L., Das, Abhik, Derman, Richard J., Dhaded, Sangappa M., Figueroa, Lester, Garcés, Ana, Goldenberg, Robert L., Goudar, Shivaprasad S., Hambidge, K. Michael, Koso-Thomas, Marion, Krebs, Nancy F., Lokangaka, Adrien, McClure, Elizabeth M., Pasha, Omrana, Sridhar, Amaanti, Stolka, Kristen, Thorsten, Vanessa R., Tshefu, Antoinette, Westcott, Jamie E.   +20 more
core   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Relationship Between Maternal Behavior During Pregnancy, Birth Outcome, and Early Childhood Development: An Exploratory Study [PDF]

This study examines the relationship between maternal behavior during pregnancy, birth outcomes, and early childhood development. Specifically, in the context of four measures of maternal behavior during pregnancy (maternal smoking, drinking, prenatal ...
Dale J. Poirier, Kai Li
core