Results 101 to 110 of about 788,741 (309)

The Effects of Early Maternal Employment on Child Development in the UK [PDF]

This paper uses data from the ALSPAC cohort of 12000 births to explore the effects of early maternal employment on child cognitive and behavioural outcomes.
Elizabeth Washbrook, Paul Gregg
core  

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

Effect of continuity of team midwifery care on maternal and neonatal outcomes: a quasi-experimental study in Iran

Scientific Reports
Midwife-led continuity of care models have been linked to better clinical outcomes in certain developed countries. However, there is a paucity of research on these models in developing nations.
Sholeh Shahinfar, Parvin Abedi, Mahin Najafian, Zahra Abbaspoor, Eesa Mohammadi, Narges Alianmoghaddam, Elham Maraghi   +6 more
doaj   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Coronavirus disease 2019 in pregnancy: clinical manifestations, maternal, and perinatal outcomes

Zanco Journal of Medical Sciences
Background and objective: The current COVID-19 pandemic has become a main health threat worldwide and concerns have been raised regarding the effect of the Covid-19 infection on the wellbeing of pregnant women and their unborn baby.
Asan Nashaat Khaleel, Nagham Younus Alhur   +1 more
doaj   +1 more source

Intrafamily Resource Allocations: A Dynamic Model of Birth Weight [PDF]

This paper estimates a model of dynamic intrahousehold investment behavior which incorporates family fixed effects and child endowment heterogeneity. This framework is applied to large American and British survey data on birth outcomes, with focus on the
Del Bono, Emilia, Ermisch, John, Francesconi, Marco   +2 more
core  

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Immigration and Adverse Pregnancy Outcomes in an Italian Free Care Hospital

International Journal of Women's Health, 2021
Giuseppe Caruso,1 Eleonora Marcoccia,1,2 Roberto Brunelli,1 Miriam Candelieri,1 Michele Carlo Schiavi,1 Ilaria Zannini,1 Seila Perrone,1 Oriana Capri,1 Ludovico Muzii,1 Giuseppina Perrone,1 Paola Galoppi1 1Department of Maternal and Child Health and ...
Caruso G, Marcoccia E, Brunelli R, Candelieri M, Schiavi MC, Zannini I, Perrone S, Capri O, Muzii L, Perrone G, Galoppi P   +10 more
doaj  

Ultrasonographic Evaluation of Uterine LSCS Scar and its Impact on Maternal Outcomes: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The evaluation of uterine scars following Caesarean Section (CS) is essential for predicting delivery outcomes, particularly in patients considering Vaginal Birth After Caesarean (VBAC) or those undergoing repeat Lower Segment Caesarean ...
Hemant Deshpande, Rohit Dimbar, Shriraj Katakdhond, Saba Chaudhary   +3 more
doaj   +1 more source