Results 121 to 130 of about 236,603 (296)

Psychological Impact of Autism Screening on Caregivers

Autism Research, EarlyView.
ABSTRACT Autism screening in childhood is common, yet little is known about its potential psychological impact on caregivers. The U.S. Preventive Services Task Force, an independent national panel of disease prevention experts, stated that this gap in knowledge limited their ability to endorse universal autism screening.
Ramkumar Aishworiya, Devon Gangi, Van Kim Ma, Chandni Parikh, Nor Azyati Yusoff, Narueporn Likhitweerawong, Sally Ozonoff   +6 more
wiley   +1 more source

Setting up mother–infant pair lactation studies with biobanking for research according to regulatory requirements

British Journal of Clinical Pharmacology, EarlyView.
Within the ConcePTION project we set out to design two mother–infant pair studies collecting breast milk and plasma from the mother and plasma from the infant (for metformin and prednisolone) in order to demonstrate the premises and conditions for investigating potential drug transfer in association with breastfeeding.
Mats Hansson, Ida Björkgren, Jenny Svedenkrans, Helena Backman, Jarl Hellman, Linda Englund‐Ögge, Mikaela Magnusson, Inger Lindström, Andrea Wutte, Erica Sundell, Pawel Baranczewski, Laura Shaughnessy   +11 more
wiley   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Women or Children? Intra-household redistribution under gender-asymmetric altruism [PDF]

In developing societies, social norms typically ascribe differential weights to paternal, maternal and communal (or state) contributions to children’s expenses. Individuals internalize these valuations. I examine a Cournot model of voluntary contribution
Indraneel Dasgupta
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Developing medication independence: The experience of UK teenagers

British Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins, Charlotte King, Louis Bioletti, Tsegay Gebru, Alder Hey Research Ambassadors, Daniel B. Hawcutt   +5 more
wiley   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Depressive, anxiety symptoms and their co-occurrence among women seeking antenatal care in Bangladesh

Scientific Reports
Anxiety and depression are significant concerns among antenatal women in Bangladesh. Despite the critical need for tailored mental health care in health facilities, studies on these symptoms in this demographic remain lacking.
Md Hafizur Rahman, Ridwana Maher Manna, Nasimul Ghani Usmani, Pradip Chandra, Md. Abdullah Al Mamun, Md Robed Amin, Maruf Ahmed Khan, Helal Uddin Ahmed, S. M. Hasibul Islam, Md. Shariful Islam, Tasnu Ara, Ema Akter, Anisuddin Ahmed, Mohammad Sohel Shomik, Shams El Arifeen, Aniqa Tasnim Hossain, Ahmed Ehsanur Rahman   +16 more
doaj   +1 more source

Foundations for enhanced maternity data collection and reporting in Australia: national maternity data development project - stage 1 [PDF]

Findings from a project aimed at building a more comprehensive and consistent national data collection for maternal and perinatal health are presented in this report.

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