Results 111 to 120 of about 3,183,824 (240)

Antibody Conjugates via Disulfide Bridging: Towards therapeutic and diagnostic applications [PDF]

, 2015
Antibodies play a prominent role in chemical and biological research and the largest application of chemical bioconjugation reagents is in the production of antibody conjugates.
Hull, EA
core  

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Field Monitoring of Colostral BVDV-, BoHV-1-, and BRSV-Specific Serum Antibody Levels in Dairy Calves from Birth to Weaning Fed with Pasteurized Colostrum Pools Obtained from Vaccinated Dams

Vaccines
Background/Objectives: This study aimed to determine the changes in BVDV (bovine viral diarrhea virus), BoHV-1 (bovine herpesvirus-1), and BRSV (bovine respiratory syncytial virus) antibody levels until weaning in calves who ingested colostrum from ...
Veysel Soydal Ataseven, Ufuk Kaya, Müge Doğan, Sultan Şengül, Seda Turan, Fatma Türkarslan Akbaba, İsmail İlker Kocaer   +6 more
doaj   +1 more source

Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis

Annals of Neurology, EarlyView.
Objective As leptomeningeal metastasis (LM) has a poor prognosis, reliable cerebrospinal fluid (CSF) diagnostic biomarkers are urgently needed. This study evaluated the diagnostic value of CSF growth differentiation factor 15 (GDF15) in LM from lung adenocarcinoma (LUAD) and breast cancer (BC).
Haoyu Ruan, Jie Li, Fuhai Wang, Lei Zhang, Jie Luo, Yuan Mu, Ting Wang, Yuqing Wu, Jingping Liu, Yunyun Ning, Xuan Deng, Ming Guan, Jian Xu   +12 more
wiley   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Maternally Derived Transferrin in Pigeon Squabs

, 1971
With the use of genetically marked transferrin, a major portion of circulating transferrin from a newly hatched squab was found to be derived from the mother through the egg. The transfer is not through the parental crop milk.
Frelinger, Jeffrey A.
core  

Priming of immune responses to hepatitis B surface antigen in young mice immunized in the presence of maternally derived antibodies

, 2001
Early vaccination is necessary to protect infants from various infectious diseases. However, this is often unsuccessful largely due to the immaturity of the neonatal immune system.
McCluskie, M J, Brazolot Millan, CL, Weeratna, RD, Siegrist, Claire-Anne, Davis, H L   +4 more
core   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Molecular characterization of chicken anemia virus and evaluation of maternally derived antibodies defense against commercially available vaccines

Beni-Suef University Journal of Basic and Applied Sciences
Background Chicken infectious anemia is a young chicken’s infection caused by a single-strand DNA gyrovirus and marked by aplastic anemia, lymphoid organs atrophy, and immunosuppression, causing severe financial losses to the poultry production.
Amal R. Abdel Aziz, Kh. M. Elbayoumi, Sanaa S. A. Awad, Samah M. Mosad, Kamel I. Abou El-Azm   +4 more
doaj   +1 more source

PRRSV specific antibody response.

, 2017
The figure illustrates the reactivity of maternally derived antibody, and vaccine derived antibody to PRRSV in plasma detected by ELISA. The optical density (OD) values in the Y-axis represents sample to positive (S/P) ratio, and a S/P value of 0.4 was ...
Muhammad Jasim Uddin (413002), Dawit Tesfaye (79384), Michael Hoelker (479275), Md. Aminul Islam (3825805), Christine Große-Brinkhaus (412998), Maren Julia Pröll (3825811), Ernst Tholen (79379), Karl Schellander (79383), Christiane Neuhoff (412997), Sharmin Aqter Rony (3825808)   +9 more
core   +1 more source