Results 141 to 150 of about 2,431,634 (302)

Hospital Review photo

, 1982
Colour photo of three nurses, two in costume, during the Hospital ...
Modbury Hospital
core  

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Modbury Hospital Foundation brochure

Brochure for the Modbury Hospital ...
Modbury Hospital
core   +1 more source

Risk factors associated with birth asphyxia at Pumwani Maternity Hospital, Nairobi, Kenya: a case-control study. [PDF]

Front Pediatr
Wagathu R, Orwa J, Kiraithe P, Ongeso A, Maina E, Omondi DG, Mutwiri B, Guetterman T.   +7 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Trends in Use of Antiseizure Medicines in Women With Epilepsy in Pregnancy During 2018-2023 in an Irish Maternity Hospital: A Cohort Study. [PDF]

Obstet Gynecol Int
Devin JE, O'Shaughnessy F, Cleary BJ, Donnelly JC, Maher N.   +4 more
europepmc   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Prevalence of and factors associated with obesity during pregnancy in Ireland 2013-2022: a retrospective observational study from a large tertiary maternity hospital. [PDF]

BMJ Public Health
Cosgrave EJ, Germaine M, Naughton P, Brennan MM, Kearney PM, Healy G, Egan B, Turner MJ, Buckley C, O'Higgins AC.   +9 more
europepmc   +1 more source

A Plea for a Pro-Maternity Hospital [PDF]

BMJ, 1901
openaire   +2 more sources

Modbury Hospital Room photos

, 1999
Colour photos of rooms in Modbury Hospital before any tables or equipment was in ...
Modbury Hospital
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