Results 161 to 170 of about 2,431,634 (302)

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

Knowledge, Practice, and Health System Challenges in the Management of Pre-Eclampsia: A Cross-Sectional Study of Midwives at Princess Christian Maternity Hospital. [PDF]

open access: yesInt J Womens Health
Torto AG   +11 more
europepmc   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

open access: yesAdvanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang   +14 more
wiley   +1 more source

On Exposure Definition and Temporal Interpretation in the Reported Association Between Number of Pregnancies and Rheumatoid Arthritis [Response to Letter]

open access: yesInternational Journal of Women's Health
Wenjie Sheng, Zhengguang Hu, Zhaokai Ma, Qinwen Feng, Nianmei Chen Department of Women’s Health, Shanghai Putuo Maternity and Infant Health Hospital, Shanghai, 200062, People’s Republic of ChinaCorrespondence: Nianmei Chen, Department
Sheng W, Hu Z, Ma Z, Feng Q, Chen N
doaj  

Hand hygiene compliance among healthcare workers at a tertiary maternity hospital in Sierra Leone: a cross-sectional study. [PDF]

open access: yesAntimicrob Resist Infect Control
Tengbe SM   +6 more
europepmc   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly

open access: yesAdvanced Science, EarlyView.
LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang   +6 more
wiley   +1 more source

Modbury Hospital Cashier photo

open access: yes
Large Colour photo of a man talking to the cashier in the Modbury Hospital ...
Modbury Hospital
core   +1 more source

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