Results 191 to 200 of about 7,910 (205)

Coclique level structure for stochastic chemical reaction networks. [PDF]

J Math Biol
Bruno S, Fu Y, Campos FA, Del Vecchio D, Williams RJ.   +4 more
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

Artificial Intelligence in the Management and Treatment of Pediatric Burns: A Narrative Review of Current Applications and Future Directions. [PDF]

Cureus
Shabbir R, Preda E, Multani HK, Akinjaiyeju T, Gagadam S, Alkiswani A, Burger Md J.   +6 more
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

Integrated Genomic and Functional Characterization of Palmitoylation in Clear Cell Renal Cell Carcinoma. [PDF]

Hum Mutat
Zhang D, Zhang K, Deng M, Ma J, Zhu J, Shen S, Xie J, Chen C.   +7 more
europepmc   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Using Machine Learning Methods to Predict Cognitive Age from Psychophysiological Tests. [PDF]

Healthcare (Basel)
Tyurina DD, Stasenko SV, Lushnikov KV, Vedunova MV.   +3 more
europepmc   +1 more source

Temporal and spatial dynamics of Net Primary Productivity and prediction of wetland carbon sequestration potential on the Tibetan Plateau. [PDF]

PeerJ
Cao L, Dong S, Wang Y, Li X, Zhao Y, Ma D, Pubu Z, Ma H, Li W, Cao P.   +9 more
europepmc   +1 more source

Mathematical Analysis for a Class of Stochastic Copolymerization Processes. [PDF]

Bull Math Biol
Anderson DF, Ma J, Gagrani P.
europepmc   +1 more source

Social Contributors to Differences in Math Course Attainment Among Adolescents with and without Learning Disabilities and ADHD. [PDF]

Soc Sci Res
Shifrer D, Frederick A, Freeman DM, Ellefritz HS, Springer R.   +4 more
europepmc   +1 more source