Results 31 to 40 of about 7,910 (205)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Energy Consumption Optimization of Multi-Dimensional U-Nets on CGLA

open access: yesIEEE Access
The increasing demand for energy-efficient medical image processing has highlighted the limitations of traditional GPU-based solutions, particularly in mobile or remote scenarios where power consumption and computational efficiency are critical.
Duong Thi Sang   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Explanations for Neural Networks by Neural Networks

open access: yesApplied Sciences, 2022
Understanding the function learned by a neural network is crucial in many domains, e.g., to detect a model’s adaption to concept drift in online learning. Existing global surrogate model approaches generate explanations by maximizing the fidelity between
Sascha Marton   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Biblioteca Digital: a experiência do Impa

open access: yesCiência da Informação, 2001
Relato da experiência do Impa na informatização de sua biblioteca, utilizando o software Horizon, e na construção de um servidor de preprints (dissertações de mestrado, teses de doutorado e artigos ainda não publicados) através da participação no projeto
Maria Cecília Pragana Chataignier   +1 more
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

ARU$^{2}$-Net: A Deep Learning Approach for Global-Scale Oceanic Eddy Detection

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Ocean eddies have a significant impact on marine ecosystems and the climate because they transport essential substances in the ocean. Detection of ocean eddies has become one of the most active topics in physical ocean research. In recent years, research
Junmin Geng   +4 more
doaj   +1 more source

DyCC-Net: Dynamic Context Collection Network for Input-Aware Drone-View Object Detection

open access: yesRemote Sensing, 2022
Benefiting from the advancement of deep neural networks (DNNs), detecting objects from drone-view images has achieved great success in recent years. It is a very challenging task to deploy such DNN-based detectors on drones in real-life applications due ...
Yue Xi   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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