Results 71 to 80 of about 2,964,590 (287)

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

On Concrete Spectral Properties of a Twisted Laplacian Associated with a Central Extension of the Real Heisenberg Group

Advances in Mathematical Physics, 2017
We consider the special magnetic Laplacian given by Δν,μ=4∑j=1n∂2/∂zj∂zj¯+2iνE+E¯+n+2μE-E¯-ν2+μ2z2. We show that Δν,μ is connected to the sub-Laplacian of a group of Heisenberg type given by C ×ω Cn realized as a central extension of the real Heisenberg ...
Aymane El Fardi, Allal Ghanmi, Ahmed Intissar   +2 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Tasks of practical content as a means of qualitative mathematical training of education seekers

Науковий Вісник Південноукраїнського Національного Педагогічного Університету імені К. Д. Ушинського
In recent years, interest in mathematics among secondary school students in Ukraine has decreased significantly. In the conditions of active development of information technologies in the world knowledge of mathematics, logical thinking and analytical ...
Bilichenko Roman, Konareva Svitlana, Tkachenko Maryna, Traktynska Viktoriia   +3 more
doaj   +1 more source

R 2 corrected AdS2 holography

Journal of High Energy Physics, 2021
We approach the problem of constructing an explicit holographic dictionary for the AdS2/CFT1 correspondence in the context of higher derivative gravitational actions in AdS2 space-times.
Pedro Aniceto, Gabriel Lopes Cardoso, Suresh Nampuri   +2 more
doaj   +1 more source

Mathematical analysis [PDF]

, 2014
У курсі математичного аналізу студент має також отримати строге наукове обґрунтування ряду питань, перше уявлення про які він одержав в шкільному курсі математики: поняття функції, границі, неперервності, похідної, інтеграла та їх застосування.
Астаф'єва, Марія Миколаївна
core  

Tumor growth instability and the onset of invasion

, 2005
Motivated by experimental observations, we develop a mathematical model of chemotactically directed tumor growth. We present an analytical study of the model as well as a numerical one.
A. H. Nayfeh, A. J. Ekstrand, A. J. Ekstrand, A. Wells, A.-L. Barabási, Carmen Molina-París, D. S. Jones, H. M. Byrne, J. A. Sherratt, J. P. Freyer, J. P. Freyer, M. J. Holmes, M. R. Chicoine, M. R. Chicoine, Mario Castro, P. C. Fife, P. Grindrod, R. K. Jain, S. H. Strogatz, S. Koochekpour, Thomas S. Deisboeck   +20 more
core   +1 more source

Physician‐Scientist Pipeline for Pediatric Rheumatology: The Current Landscape and Future Perspectives

Arthritis Care &Research, EarlyView.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu, Linda T. Hiraki, Mara L. Becker   +2 more
wiley   +1 more source

Generalized multidimensional Hilbert transforms in Clifford analysis

International Journal of Mathematics and Mathematical Sciences, 2006
Two specific generalizations of the multidimensional Hilbert transform in Clifford analysis are constructed. It is shown that though in each of these generalizations some traditional properties of the Hilbert transform are inevitably lost, new bounded ...
Fred Brackx, Bram De Knock, Hennie De Schepper   +2 more
doaj   +1 more source