Beyond Body Weight: A Comprehensive Review of Allometric Scaling in Drug Development for Human Dose Predictions. [PDF]
PharmaceuticsMallillin MC +6 more
europepmc +1 more source
Advancing pharmacometrics in Africa—Transition from capacity development toward job creation
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai +10 more
wiley +1 more source
Insights and perspectives into the etiology of TKI-induced cardiotoxicity. [PDF]
ASPET DiscovXu V +6 more
europepmc +1 more source
Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma
CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou +4 more
wiley +1 more source
Integrating iHEC into standardized residency training for chronic disease management: a structural equation analysis of competency outcomes via digital health platforms. [PDF]
Front Public HealthXie D +5 more
europepmc +1 more source
Impact of Packaging and Recycling Systems on Material Recirculation: A Stage‐Decomposition Model
Packaging Technology and Science, EarlyView.A system‐level view emerges from decomposing recycling into four stages (participation, collection, sorting and process yield), diagnosing constraints and targeting interventions. Cumulative equivalent uses (CEUs) quantify long‐term retention, revealing marginal improvements at high baselines generate disproportionately larger gains than low‐baseline ...
Diogo Figueirinhas +3 more
wiley +1 more source
PK-Informed Microphysiological Systems: From Dynamic Dosing to Quantitative In Vitro-In Vivo Translation. [PDF]
PharmaceuticsKang SJ +10 more
europepmc +1 more source
Dumpsite Seabed Characterization of the San Pedro Basin, CA, From Autonomous Vehicle Observations
Journal of Field Robotics, EarlyView.ABSTRACT A wide‐area seabed survey was conducted using autonomous underwater vehicles (AUVs) in a known dumpsite off the coast of Southern California that has been found to have widespread sediment contamination from the chemical dichlorodiphenyltrichloroethane (DDT).
Ryan A. McCarthy +4 more
wiley +1 more source
Individual-Eye Pharmacokinetics of Intravitreal Ranibizumab: Linking Ocular Geometry to Drug Retention Using MRI and Modeling. [PDF]
Invest Ophthalmol Vis SciLamirande P +10 more
europepmc +1 more source
Is It Political? Science Teachers' Perspectives on GSD‐Inclusive Science Teaching
Science Education, EarlyView.ABSTRACT Teaching is often framed as neutral and apolitical, yet scholarship has long documented its entanglement with power, identity, and ideology. Despite growing attention to the sociopolitical dimensions of science education, less is known about what science teachers themselves understand as political and how those understandings shape where they ...
Gary W. Wright, Victoria Barron
wiley +1 more source