Results 41 to 50 of about 454,972 (267)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Scientific ReportsColon cancer is a high-risk malignant tumor worldwide. To address the limited efficacy and overlapping toxicity of current chemoimmunotherapy, this study establishes a fractional-order colon cancer model with a core architecture capturing the probiotics-
Ruilei Tai +3 more
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Mathematical model for knowledge testing
Lietuvos Matematikos Rinkinys, 2008 There is a mathematical model for obtaining test responses probability distribution proposed. This enables to formulate recomendations for selection of test items for different groups of tested population according to their attainment level.
Aleksandras Krylovas, Natalja Kosareva
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A Mathematical Model of a Micrometastasis [PDF]
Computational and Mathematical Methods in Medicine, 1997 Experimental evidence indicates that tumour metastases can exist for long periods in a dormant state, with cell proliferation balancing cell death. However, this balance can be upset, by removing the primary tumour for instance, which causes the metastasis to grow, or by adminstering a substances inhabiting angiogenesis which causes the metastasis toi ...
Malcolm Bloor, Michael Wilson
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
ON A MATHEMATICAL SECURITY MODEL
Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016 A model of system maintenance which ensures secure operation of the system is investigated. To this end, mathematical model of a controlled semi-Markov process with catastrophes is used.
Victor Kashtanov, Ekaterina Dlinnova
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A View of Mathematical Modeling in Mathematics Education
, 2013 Journal of Mathematics Education at Teachers College, 2013: Proceedings: Conference on Mathematical ...
Henry Pollak, Sol Garfunkel
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source