Results 51 to 60 of about 2,925,273 (287)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Mathematical model for pulsed chemotherapy

ITM Web of Conferences, 2015
A pulsed chemotherapeutic treatment model is investigated in this work. We prove the existence of nontrivial periodic solutions by the mean of Lyapunov-Schmidt bifurcation method of a cancer model. In this model we consider the case of application of two
Lakmeche Ahmed, Helal Mohamed, Lakmeche Abdelkader   +2 more
doaj   +1 more source

ON A MATHEMATICAL SECURITY MODEL

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2016
A model of system maintenance which ensures secure operation of the system is investigated. To this end, mathematical model of a controlled semi-Markov process with catastrophes is used.
Victor Kashtanov, Ekaterina Dlinnova
doaj   +1 more source

Mathematical model for predicting human vertebral fracture [PDF]

, 1973
Mathematical model has been constructed to predict dynamic response of tapered, curved beam columns in as much as human spine closely resembles this form. Model takes into consideration effects of impact force, mass distribution, and material properties.
Benedict, J. V.
core   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Mathematical model of thermal aggregates [PDF]

Acta Montanistica Slovaca, 1998
Tepelné agregáty môžme charakterizova jako priemyselné pece s ve¾kou spotrebou energie. Jednou z možných ciest zníženia spotreby energie je optimalizácia a priebežné riadenie priemyselných tepelných agregátov pomocou simulaèných modelov. Východiskom
Kostúr Karol, Pokorný Imrich
doaj  

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

A fractal-fractional mathematical model for COVID-19 and tuberculosis using Atangana–Baleanu derivative

Mathematical and Computer Modelling of Dynamical Systems
This study aims to develop a compartmental epidemiological model for the co-infection of COVID-19 and tuberculosis, incorporating a Holling type II treatment rate for individuals with tuberculosis, COVID-19, and dual infections while considering ...
T. Gunasekar, S. Manikandan, M. Suba, Ali Akgül   +3 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Mathematical model of environmental waters purification [PDF]

E3S Web of Conferences, 2019
This article describes the use of the stochastic approach, in particular, mass service theory and the development of its methods, adapted directly to the coagulation process as a mathematical tool.
Skolubovich Yuri, Skolubovich Alexey, Volkov Dmitry, Krasnova Tamara, Gogina Elena   +4 more
doaj   +1 more source