Results 181 to 190 of about 1,951,824 (276)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) C.M. de Lange   +26 more
wiley   +1 more source

Non-commutative structures of brain and cognition: quantum and contextual probability as a translational framework. [PDF]

Front Hum Neurosci
Emori H, Khrennikov A, Iriki A.
europepmc   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

How to Foster Challenging Interdisciplinary Collaborations: Can Philosophy Support Neuroscientists? [PDF]

Eur J Neurosci
Kunze M, Brun C, Badaut J, Darnaudéry M, Gross F, Peltier L, Pradeu T, Sarto-Jackson I, Konsman JP.   +8 more
europepmc   +1 more source

Neural Local Inter‐reflection Modeling for Garment Fold Rendering

Computer Graphics Forum, EarlyView.
Abstract Realistic garment rendering requires simulating complex multi‐bounce light paths within intricate fold geometries. In these regions, conventional path tracing is computationally expensive as light becomes trapped, necessitating high bounce counts for convergence.
Jooeun Son, Nuri Ryu, Gyoonseo Kim, Joo Ho Lee, Seungyong Lee   +4 more
wiley   +1 more source

Symmetry-based derivation of neuronal membrane dynamics: a Lie group approach to action potential generation. [PDF]

Front Neurosci
Melendy RF, Blue DH.
europepmc   +1 more source

Problems in comparing tobacco regulatory models and excise when only two countries are considered

Addiction, EarlyView.
Simon Chapman, Sam Egger, Becky Freeman
wiley   +1 more source

Validation of the QOLIBRI‐KIDDY self‐rated and proxy‐rated questionnaires after paediatric traumatic brain injury

Developmental Medicine &Child Neurology, EarlyView.
This validation study examines the final versions of the QOLIBRI‐KIDDY (self‐report) and QOLIBRI‐KIDDY‐Proxy (parent‐report) questionnaires, designed to measure health‐related quality of life in children aged 6–7 following traumatic brain injury. Both versions cover six domains, demonstrate reliable psychometric properties, and give children a voice ...
Nicole von Steinbuechel, Marina Zeldovich, Anna C. Mayer, Lena Schemet, Michael von Rhein, Daniela Jepathavakumar, Christian Auer, Anna Buchheim, Katrin Cunitz, The QOLIBRI‐KIDDY Study Group, S. Berweck, M Kieslich, M. Henrich, M. Lendt, U. Wartemann, J. Suss, J. Driemeyer, D. Pinggera, V. Schoen, P. Geiger, C. Thomé   +20 more
wiley   +1 more source

Sensorimotor numerosity uniquely supports arithmetic development in children. [PDF]

Iperception
Anobile G, Martelli S, Bieber E, Tinelli F, Ditano S.   +4 more
europepmc   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid, Peter G. Hains, Velda X. Han, Jingya Yan, Michael Griffiths, Ignatius Pang, Sushil Bandodkar, Phillip J. Robinson, Russell C. Dale   +8 more
wiley   +1 more source