Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
The evolution of public health statistical modeling approaches and how to advance their incorporation into modern arboviral surveillance. [PDF]
McCarter M +5 more
europepmc +1 more source
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani +7 more
wiley +1 more source
Recognizing ALBI Grade in Child-Pugh A Patients at a Glance: Mathematical Simulation and Large-Scale Clinical Validation. [PDF]
Chuang PH, Ding YJ, Lin CY, Lu SN.
europepmc +1 more source
Nonlocal Conduction in a Metawire
A 1D metawire composed of twisted copper wires is designed and realized. This metamaterial exhibits pronounced effects of nonlocal electric conduction according to Ohm's law. The current at one location not only depends on the electric field at that location but also on other locations.
Julio Andrés Iglesias Martínez +3 more
wiley +1 more source
A quasi-experimental study: cultivating mathematical resilience via intervention in Chinese classrooms. [PDF]
Wang X, Madihie A.
europepmc +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source
Computational thinking as a mediator between modeling self-efficacy and flexible thinking in pre-service science teachers. [PDF]
Beyazhancer R, Cepni S.
europepmc +1 more source
Practical Business Mathematics
Paul R. Rider +2 more
openaire +2 more sources
AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll +19 more
wiley +1 more source

