Results 41 to 50 of about 626,729 (334)
Modelling of mathematical programs: An analysis of strategy and an outline description of a computer assisted system [PDF]
The salient components of the mathematical programming modeling activity are first analysed. Earlier generation systems such as program generators and procedural (modelling) languages are briefly discussed.
Lucas, CA, Mitra, G
core
Several types of types in programming languages [PDF]
Types are an important part of any modern programming language, but we often forget that the concept of type we understand nowadays is not the same it was perceived in the sixties. Moreover, we conflate the concept of "type" in programming languages with
A Church +19 more
core +5 more sources
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Positive Mathematical Programming and Risk Analysis
In 1956, Freund introduced the analysis of agricultural price risk in a mathematical programming framework. His discussion admitted only constant absolute risk aversion.
Quirino Paris
doaj +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Cost function and positive mathematical programming
A line of research in Positive Mathematical Programming (PMP) has pursued the goal of estimating a cost function capable of reproducing the base-year results in a sample of farms.
Quirino Paris
doaj +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Tools for reformulating logical forms into zero-one mixed integer programs (MIPS) [PDF]
A systematic procedure for transforming a set of logical statements or logical conditions imposed on a model into an Integer Linear Programming (ILP) formulation or a Mixed Integer Programming (MIP) formulation is presented.
Lucas, CA, Mitra, G, Moody, S
core
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu +2 more
wiley +1 more source

