We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Integrated and Differentiated Spaces of Triangular Fuzzy Numbers
Fuzzy sets are the cornerstone of a non-additive uncertainty theory, namely possibility theory, and of a versatile tool for both linguistic and numerical modeling.
Kirişci, Murat
core +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Composites with a periodic structure: mathematical analysis and numerical treatment
The authors treat the solution of a partial differential equation describing the behaviour of composites that have a periodic structure. The equation has highly oscillatory periodic coefficients. The technique of homogenization which is appropriate for specific applications and which can be used as the basis for an adaptive model is discussed.
Ivo Babuška, R. C. Morgan
openaire +2 more sources
Will gravitational waves confirm Einstein's General Relativity? [PDF]
Even if Einstein's General Relativity achieved a great success and overcame lots of experimental tests, it also showed some shortcomings and flaws which today advise theorists to ask if it is the definitive theory of gravity.
Ch. Tsitouras +3 more
core +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Matrix Structure Exploitation in Generalized Eigenproblems Arising in Density Functional Theory
In this short paper, the authors report a new computational approach in the context of Density Functional Theory (DFT). It is shown how it is possible to speed up the self-consistent cycle (iteration) characterizing one of the most well-known DFT ...
Bientinesi, Paolo +4 more
core +1 more source
Guest editors’ preface to the special issue devoted to the 2nd International Conference “Numerical Computations: Theory and Algorithms”, June 19–25, 2016, Pizzo Calabro, Italy [PDF]
This special issue of the Journal of Global Optimization contains twelve high-quality research papers devoted to different aspects of global optimization such as theory, numerical methods and real-life applications.
De Leone, Renato +2 more
core +1 more source
ICU‐EEG Pattern Detection by a Convolutional Neural Network
ABSTRACT Objective Patients in the intensive care unit (ICU) often require continuous EEG (cEEG) monitoring due to the high risk of seizures and rhythmic and periodic patterns (RPPs). However, interpreting cEEG in real time is resource‐intensive and heavily relies on specialized expertise, which is not always available.
Giulio Degano +5 more
wiley +1 more source
Mathematical and numerical analysis for coagulation-fragmentation equations [PDF]
This thesis is devoted to the mathematical and numerical analysis for the continuous coagulation-fragmentation equation. This is a partial integro-differential equation. There have been several investigations of existence and uniqueness of solutions to the coagulation and binary fragmentation equation with different classes of kernels.
openaire +2 more sources

