SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
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Effects of students' mathematics learning strategy and perceived task difficulty on their achievement of mathematics. [PDF]
Eka WD, Tola TT, Negasi RD.
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The cerebellum-driven social basis of mathematics: implications for one-on-one tutoring of children with mathematics learning disabilities. [PDF]
Vandervert L, Moe K.
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Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han +10 more
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Enhancing Mathematics Learning for Students with Intellectual and Developmental Disabilities in China: A Qualitative Study of Instructional Support. [PDF]
Yan T, Jin Y.
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Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
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Engagement patterns of middle school students with AI teachable agents in mathematics learning. [PDF]
Liu Z +5 more
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Self-regulated learning, online mathematics learning engagement, and perceived academic control among Chinese junior high school students during the COVID-19 pandemic: A latent profile analysis and mediation analysis. [PDF]
Dai W, Li Z, Jia N.
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This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv +12 more
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