Results 111 to 120 of about 746,215 (354)
Phosphatidylserine polarization is required for proper Cdc42 localization and for development of cell polarity. [PDF]
, 2010 We used genetically-encoded fluorescent probes to visualize the distribution of phosphatidylserine (PS) in live S. cerevisiae. The majority of the PS was found to reside in the cytosolic leaflet of the plasma membrane.
Gregory Fairn, Sergio Grinstein
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Latin American Journal of Aquatic Research, 2010 Se estableció la forma en que los machos del camarón Rhynchocinetes typus transfieren los espermatoforos durante la cópula. La fecundación es externa y durante el apareamiento, el primer y segundo par de pleopodos masculinos tienen una activa ...
Rubí Martínez, Enrique Dupré
doaj
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Impact of diverse musical genres on blood-feeding and mating behavior in Aedes aegypti mosquitoes
Journal of Vector Borne DiseasesBackground & objectives: Sound plays an important role in mosquito foraging and sexual interactions. Mosquitoes utilize acoustic signals for host location, sexual recognition, and mating, which is achieved through the rhythmic beating of their wings to ...
Chew Yan Ni +5 more
doaj +1 more source
A Comparison of Two Methods of Quantifying Mating Success in Low Density Gypsy Moth (Lymantria dispar) Populations [PDF]
, 2018 The gypsy moth (Lymantria dispar) is a defoliating pest native to Europe and invasive to North America. The gypsy moth is subject to depressed mating success in low density populations, which may restrict spread of the forest pest.
Barry, Alexandra +2 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Invariant Jordan curves in the Julia sets of rational maps
AIMS MathematicsWe give a way to construct invariant Jordan curves in the Julia sets of rational maps that are not boundaries of Fatou components.
Xiuming Zhang
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Royal Society Open ScienceThe molecular mechanisms underlying the maturation of innate reward behaviours remain poorly understood. We have identified a sexually dimorphic innate reward behaviour in Drosophila melanogaster that varies depending on the age, sex and mating status in
Antonio Marini-Davis +5 more
doaj +1 more source