Results 171 to 180 of about 221,203 (298)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Mating system of free-ranging domestic dogs and its consequences for dog evolution. [PDF]

Proc Natl Acad Sci U S A
Car C, Adavoudi R, Berghänel A, Vanderheyden M, Moura AE, Range F, Cimarelli G, Lazzaroni M, Dale R, El Berbri I, Spatola GJ, Mousseau TA, Marshall-Pescini S, Pilot M.   +13 more
europepmc   +1 more source

The selfing syndrome and beyond: diverse evolutionary consequences of mating system transitions in plants. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2022
Tsuchimatsu T, Fujii S.
europepmc   +1 more source

Low-Impact Mating System for Docking Spacecraft

, 2008
A document describes a low-impact mating system suitable for both docking (mating of two free-flying spacecraft) and berthing (in which a robot arm in one spacecraft positions an object for mating with either spacecraft).
Lewis, James L., Morales, Ray, Robertson, Brandan, Carroll, Monty B., Le, Thang   +4 more
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Investigating the consequences of the mating system for drug resistance evolution in <i>Caenorhabditis elegans</i>. [PDF]

Proc Biol Sci
Trubenová B, Hellinga J, Krücken J, von Samson-Himmelstjerna G, Schulenburg H, Regoes RR.   +5 more
europepmc   +1 more source

Competitive ability depends on mating system and ploidy level across Capsella species. [PDF]

Ann Bot, 2022
Orsucci M, Yang X, Vanikiotis T, Guerrina M, Duan T, Lascoux M, Glémin S.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

THE EVOLUTION OF INSECT MATING SYSTEMS [PDF]

Evolution, 1984
Michael J. Wade, R. Thornhill, J. Alcock
openaire   +3 more sources

Exogenous hormones regulate the sequentially reproductive output in Pseudostellaria heterophylla with a chasmogamous-cleistogamous mixed mating system. [PDF]

Sci Rep
Sun Q, Wu L, Zhao JM, Zhang YW.
europepmc   +1 more source