Results 181 to 190 of about 458,493 (298)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Mating system of <i>Biomphalaria sudanica,</i> a vector of <i>Schistosoma mansoni</i>. [PDF]

Curr Res Parasitol Vector Borne Dis
Olson J, Pennance T, Spaan JM, Odiere MR, Tennessen JA, Steinauer ML.   +5 more
europepmc   +1 more source

Populational Evidence Supports a Monogomous Mating System in Five Species of Snapping Shrimps of the Genus Alpheus (Caridea: Alpheidae). [PDF]

Zool Stud, 2022
Costa-Souza AC, Souza JRB, Almeida AO.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Editorial: The impacts of the mating system and inbreeding depression in natural plant populations and crop systems. [PDF]

Front Plant Sci
Brunet J, Kelly JK.
europepmc   +1 more source

Do annual and perennial populations of an insect-pollinated plant species differ in mating system? [PDF]

Ann Bot, 2021
Ma Y, Barrett SCH, Wang FY, Deng JC, Bai WN.   +4 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Urbanization Alters Phenology, Mating System Allocation, and Life History of <i>Impatiens capensis</i> (Balsaminaceae) via Trait-Specific Plasticity and Genetic Differentiation. [PDF]

Ecol Evol
Stanley AM, Ashman TL.
europepmc   +1 more source

Softness of selection and mating system interact to shape trait evolution under sexual conflict. [PDF]

Evolution, 2021
Li Richter XY, Hollis B.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source