Results 71 to 80 of about 454,868 (300)

Mitigating Architectural Mismatch During the Evolutionary Synthesis of Deep Neural Networks [PDF]

, 2018
Evolutionary deep intelligence has recently shown great promise for producing small, powerful deep neural network models via the organic synthesis of increasingly efficient architectures over successive generations.
Chung, Audrey, Fieguth, Paul, Wong, Alexander   +2 more
core   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

How should we measure population-level inbreeding depression? Impacts of standing genetic associations between selfing rate and deleterious mutations

Frontiers in Plant Science
Inbreeding depression (ID) is a major selective force during mating system evolution primarily contributed by highly to partially recessive deleterious mutations.
Kuangyi Xu
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Study on the reproduction of Colquhounia coccinea

Xibei zhiwu xuebao
[Objective] The torch flower (Colquhounia coccinea) exhibits a typical avian syndrome, and thus has the potential to be developed as a bird-attracting landscape plant. [Methods] With the C. coccinea populations in natural and artificial habitats as the
HUANG Meiying, DUAN Yunbo, LIANG Qiongyue, HUANG Shixun, CHEN Zhe, LIU Changqiu   +5 more
doaj   +1 more source

Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall.) Regel at the Eastern Baikal Lake shore [PDF]

Annals of Forest Research, 2008
Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila(Pall.) Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin) by means of 31 ...
E.A. Petrova, S.N. Goroshkevich, Y.S. Belokon, D.V. Politov   +3 more
doaj  

The limits of mean-field heterozygosity estimates under spatial extension in simulated plant populations [PDF]

, 2012
Computational models of evolutionary processes are increasingly required to incorporate multiple and diverse sources of data. A popular feature to include in population genetics models is spatial extension, which reflects more accurately natural ...
Allaby, Robin G., Kitchen, James
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Hard Mating Aggregation as Evidence of Polyandry in the Red‐Tailed Boa, Boa constrictor (Squamata: Boidae), in a Brazilian Caatinga Population

Ecology and Evolution
This study reports a reproductive aggregation of a female Boa constrictor with five males in the Brazilian Caatinga. The observation reinforces the evidence of a polyandrous system, favoring larger females that copulate with different males.
Selma Maria deAlmeida‐Santos, Renan Augusto Ramalho   +1 more
doaj   +1 more source

Mating system and population genetic structure of the bulldog ant Myrmecia pavida [PDF]

, 2013
Understanding the evolution of the alternative mating strategies of monandry and polyandry is a fundamental problem in evolutionary biology because of the cost-benefit trade-offs associated with mating for females.
Baer, Boris, Chappell, Paula, Hughes, William O H, Roberts, Katherine   +3 more
core   +1 more source