Results 91 to 100 of about 221,203 (298)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Inbreeding and founder cultivars contributions in low chill requirement peaches and nectarines

Crop Breeding and Applied Biotechnology, 2023
The pedigree analysis from genealogical data can estimate the inbreeding from identity-by-descent, being a powerful tool for germplasm characterization. The aim of this study was to evaluate the genetic diversity of peach and nectarine cultivars from the
Graciela da Rocha Sobierajski, Gabriel Constantino Blain, Carina Oliveira Anoni   +2 more
doaj  

Navigating Monogamy: Nonapeptide Sensitivity in a Memory Neural Circuit May Shape Social Behavior and Mating Decisions

Frontiers in Neuroscience, 2017
The role of memory in mating systems is often neglected despite the fact that most mating systems are defined in part by how animals use space. Monogamy, for example, is usually characterized by affiliative (e.g., pairbonding) and defensive (e.g., mate ...
Alexander G. Ophir
doaj   +1 more source

Male attractiveness is negatively genetically associated with investment in copulations

, 2011
In species with high male mating effort, there is a trade-off between mating effort spent in a current mating and resources left for future matings. Males are therefore expected to allocate resources prudently across successive matings.
Engqvist, Leif, Leif Engqvist, Engqvist, Leif ; https://orcid.org/   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Male mating tactics in the rose bitterling (Rhodeus ocellatus) and European bitterling (Rhodeus amarus)

, 2013
The aim of this study was to investigate the basis to male mating decisions in two related species of bitterling: Rhodeus ocellatus and R. amarus. Bitterling have a resource-based mating system; females lay eggs in the gills of live freshwater mussels ...
Casalini, Mara
core  

Genetic exchange in Trypanosoma brucei: evidence for mating prior to metacyclic stage development [PDF]

, 2005
It is well established that genetic exchange occurs between Trypanosoma brucei parasites when two stocks are used to infect tsetse flies under laboratory conditions and a number of such crosses have been undertaken.
Turner, C.M.R., Tait, A., Tweedie, A., Masiga, D., MacLeod, A.   +4 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Homosexual Pairing within a Swarm-Based Mating System: The Case of the Chironomid Midge

Psyche: A Journal of Entomology, 2011
Homosexuality has been dubbed the Darwinian paradox, because it raises the question of how behaviour that would seem to reduce the chance of successful mating can be maintained by natural selection.
Athol J. McLachlan
doaj   +1 more source

Semiochemical and Vibrational Cues and Signals Mediating Mate Finding and Courtship in Psylloidea (Hemiptera): A Synthesis

Insects, 2014
Mate finding and courtship involve complex interactions that require close coordination between individuals of the opposite gender. Well-organized signalling systems, sometimes involving a combination of signal modalities, are required to convey species ...
Umar K. Lubanga, Christelle Guédot, Diana M. Percy, Martin J. Steinbauer   +3 more
doaj   +1 more source