Results 41 to 50 of about 136,854 (259)

Stepwise recombination suppression around the mating-type locus in an ascomycete fungus with self-fertile spores.

PLoS Genetics, 2023
Recombination is often suppressed at sex-determining loci in plants and animals, and at self-incompatibility or mating-type loci in plants and fungi. In fungal ascomycetes, recombination suppression around the mating-type locus is associated with pseudo ...
Nina Vittorelli, Ricardo C Rodríguez de la Vega, Alodie Snirc, Emilie Levert, Valérie Gautier, Christophe Lalanne, Elsa De Filippo, Pierre Gladieux, Sonia Guillou, Yu Zhang, Sravanthi Tejomurthula, Igor V Grigoriev, Robert Debuchy, Philippe Silar, Tatiana Giraud, Fanny E Hartmann   +15 more
doaj   +1 more source

Combinatorics and Variety of Mating-Type Systems [PDF]

Evolution, 1989
Les differents systemes de croisement chez les fungi, les cilies, les plantes a fleur, etudie sous forme d'analyse combinatoire afin de determiner le nombre de combinaisons possibles de types de systemes de ...
J J, Bull, Craig M, Pease
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Activation of the Mating Pheromone Response Pathway of Lentinula edodes by Synthetic Pheromones

Mycobiology, 2018
Pheromone (PHB)-receptor (RCB) interaction in the mating pheromone response pathway of Lentinula edodes was investigated using synthetic PHBs. Functionality of the C-terminally carboxymethylated synthetic PHBs was demonstrated by concentration-dependent ...
Byeongsuk Ha, Sinil Kim, Minseek Kim, Hyeon-Su Ro   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Discovery and Characterization of Epichloë Fungal Endophytes from Elymus spp. in Northwest China

Microorganisms
Epichloë fungal endophytes hold promise in sustainable agriculture by fortifying cool-season grasses such as Elymus spp. against various stresses. Elymus spp. are widely distributed in Northwest China with a high incidence of endophyte infections.
Mingxiang Du, Tian Wang, Chunjie Li, Taixiang Chen   +3 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

The genetic architecture of the load linked to dominant and recessive self-incompatibility alleles in Arabidopsis halleri and Arabidopsis lyrata

eLife
The long-term balancing selection acting on mating types or sex-determining genes is expected to lead to the accumulation of deleterious mutations in the tightly linked chromosomal segments that are locally ‘sheltered’ from purifying selection.
Audrey Le Veve, Mathieu Genete, Christelle Lepers-Blassiau, Chloé Ponitzki, Céline Poux, Xavier Vekemans, Eleonore Durand, Vincent Castric   +7 more
doaj   +1 more source

Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans

mSphere, 2022
The CCAAT-binding heme activator protein (HAP) complex, comprising the DNA-binding heterotrimeric complex Hap2/3/5 and transcriptional activation subunit HapX, is a key regulator of iron homeostasis, mitochondrial functions, and pathogenicity in ...
Jin-Young Kim, Yong-Sun Bahn
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source