Results 91 to 100 of about 4,760 (206)
Analysis of matrine-type alkaloids using ESI-QTOF
, 2013 A series of six matrine-type alkaloids, including a pair of stereoisomers, was investigated using electrospray ionization quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS) in positive-ion mode.
Sun, Dong-Ming +6 more
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Frontiers in Pharmacology, 2019 Matrine, an alkaloid compound isolated from the medicinal plant Sophora flavescens, inhibits many types of cancer proliferation. However, the precise mechanism of the matrine antihuman chronic myeloid leukemia remains unclear.
Guibin Lin +7 more
doaj +1 more source
Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation. [PDF]
, 2012 Acute myeloid leukemia (AML) is a hematological malignancy characterized by a rapid increase in the number of immature myeloid cells in bone marrow. Despite recent advances in the treatment, AML remains an incurable disease.
Zhang Shenghui +17 more
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Frontiers in OncologyBackgroundMatrine is an alkaloid extracted from Sophorus beans of the legume family, and it has significant effects and a variety of pharmacological activities. Osteosarcoma(OS) is a common malignant bone tumor that is characterized by high incidence and
Xincheng Huang +5 more
doaj +1 more source
Matrin 3 and HIV Rev Regulation of mRNA [PDF]
Retrovirology, 2011 The nuclear matrix protein, MATR3, is a newly-described Rev cofactor whose mechanism of action is only starting to be revealed.
openaire +3 more sources
Matrine Restores Colistin Efficacy Against mcr-1-Carrying Escherichia coli
The emergence of mcr-1-mediated colistin resistance has become a critical global health concern, highlighting the urgent need for innovative approaches to restore colistin’s therapeutic potential.
Liang Zhao +11 more
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Alopecuroides A–E, Matrine-Type Alkaloid Dimers from the Aerial Parts of Sophora alopecuroides
, 2019 Five new matrine-type alkaloid dimers, alopecuroides A–E, were isolated from the aerial parts of Sophora alopecuroides. Alopecuroides A and B represent the first dimeric matrine-type alkaloids possessing a cyano group and an epoxy moiety. Alopecuroides C
Hai-Yan Tian (536638) +12 more
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Matrine Is Identified as a Novel Macropinocytosis Inducer by a Network Target Approach
Frontiers in Pharmacology, 2018 Comprehensively understanding pharmacological functions of natural products is a key issue to be addressed for the discovery of new drugs. Unlike some single-target drugs, natural products always exert diverse therapeutic effects through acting on a ...
Bo Zhang +6 more
doaj +1 more source
, 2018 The present study investigated the extraction and purification technology of matrine from Sophora flavescens Ait. and the inhibitory effects of matrine on human nasopharyngeal carcinoma (NPC) CNE-2 cells. The matrine was extracted from Sophora flavescens
WANG,Ming +5 more
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Matrine Inhibits Neuroblastoma Cell Proliferation and Migration by Enhancing Tribbles 3 Expression
, 2018 Neuroblastoma is a major contributor of cancer-specific mortality. Although remarkable enhancement has been achieved in the treatment of neuroblastoma in patients with early stage disease, limited progress has been made in the treatment of patients with ...
Xiancheng Kong +6 more
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