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[Pharmacokinetics and pharmacodynamics of matrine and oxymatrine].
Yao xue xue bao = Acta pharmaceutica Sinica, 1993On measuring the percentage of QTc interval prolongation, the pharmacokinetic and pharmacodynamic profiles of i.v. matrine or oxymatrine in rabbits were analyzed by combined pharmacokinetic and pharmacodynamic model. The plasma concentration--time profiles of the two drugs can be described by a two--compartment open model, and the relationship between ...
X H, Wang, S K, Huang
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[Anti-arrhythmic effects of matrine].
Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991Matrine (MT) is an alkaloid isolated from Sophra alopecuroids L. The LD50 of MT iv to mice was 72.1 mg/kg (95% CL 68.2-76.5 mg/kg). MT had significant effects on different experimental models of arrhythmias induced by aconitine, barium chloride or coronary ligation. The ECG of anesthetized rats was significantly changed after iv of MT.
B H, Zhang +4 more
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Antipruritic Effect of Matrine
Journal of Cell Signaling, 2018Mei Yu, Zongxiang Tang
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MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF
2011JIANG JIANDONG +8 more
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