Results 51 to 60 of about 27,594,235 (204)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Sampling and Mapping Chemical Space with Extended Similarity Indices
Molecules, 2023 Visualization of the chemical space is useful in many aspects of chemistry, including compound library design, diversity analysis, and exploring structure–property relationships, to name a few.
Kenneth López-Pérez +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Functionalized graphene – poly(vinyl alcohol) nanocomposites: Physical and dielectric properties
eXPRESS Polymer Letters, 2012 Chemically derivatized graphene/poly(vinyl alcohol) (PVA) nanocomposites were successfully fabricated by combination of solution processing and compression molding.
G. C. Psarras, I. Tantis, D. Tasis
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A Phylogenetic Analysis of Tribes of the Asteraceae Based on Phytochemical Data
Natural Product Communications, 2007 This work describes the first phylogenetic analysis of the entire Asteraceae based only on chemical data. The data matrix used in this study was based on a large chemical database comprising ~400 skeletal types of terpenes, coumarins, flavonoids ...
Lalita M. Calabria +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Bidirectional branch and bound for controlled variable selection. Part I: principles and minimum singular value criterion. [PDF]
, 2008 The minimum singular value (MSV) rule is a useful tool for selecting controlled variables (CVs) from the available measurements. However, the application of the MSV rule to large-scale problems is difficult, as all feasible measurement subsets need to
Kariwala, Vinay, Cao, Yi
core +1 more source
Journal of Natural Fibers, 2022 The latest environmental legislations imposed by various governments across the globe have made exceptional utilization of biodegradable (green) materials in composite structures.
Vasantha Kumar Shravanabelagola Nagaraja Setty +4 more
doaj +1 more source