An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Classification of sheep category using chemical analysis and statistical classification algorithms [PDF]
, 2011 In Australia, dentition (eruption of permanent incisors) is used as a proxy for age to define sheep meat quality. Lamb is defined as having no permanent incisors, hogget as having at least one incisor and mutton is defined as having two or more incisors.
Watkins, Peter
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
M-MATRIX-WP6.M1 - "DASHBOARDS OPERATIONAL WITHIN THE PILOT PARTICIPATING AGENCIES"
, 2022 M-MATRIX-WP6.M1 - “Dashboards operational within the pilot participating agencies” Milestone report for M1 of MATRIX ...
MATRIX
core +1 more source
A Distinguishable Role of eDNA in the Viscoelastic Relaxation of Biofilms
mBio, 2013 Bacteria in the biofilm mode of growth are protected against chemical and mechanical stresses. Biofilms are composed, for the most part, of extracellular polymeric substances (EPSs). The extracellular matrix is composed of different chemical constituents,
Brandon W. Peterson +4 more
doaj +1 more source
Extraction and Characterization of Sponge Gourd Outer Skin Fiber
Journal of Natural Fibers, 2023 Plant-derived natural fibers have recently been used as a promising reinforcement in polymer matrix composites. Fibers from the inner sponge of the luffa cylindrica fruit have been the subject of several studies as reinforcement in various polymer resins.
Felix Sahayaraj A +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Macromodel of interfacial transition layer in ceramic matrix composites
MATEC Web of Conferences, 2018 The purpose of the study is to create a macromodel of interfacial transition layer in ceramic matrix composites. Chemical and mineralogical compositions were investigated by means of X-ray fluorescence analysis and X-ray diffractometry, ceramic and ...
Stolboushkin Andrey +3 more
doaj +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Shape Memory Actuator: thermomechanical training and surface optimization of shape memory wires embedded in a polymeric matrix [PDF]
, 2011 In the first part of my work I studied the mechanical and thermal behaviour of NiTi wires and strips in order to find the best training cycle to achieve a good compromise between transformation temperatures, recovery forces and phase reversibility ...
Scoponi, Martina
core