Results 121 to 130 of about 310,012 (309)
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Factorization of some classes of matrix functions and the resolvent of a Hankel operator
, 2020 The factorization of some classes of matrix-valued functions is obtained, which yields some new results for a special class of Hankel integral operators in L-2(+).
Conceição, Ana C. +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Mersenne Matrix Operator and Its Application in $p-$Summable Sequence Space
Communications in Advanced Mathematical SciencesIn this study, it is introduced the regular Mersenne matrix operator which is obtained by using Mersenne numbers and examined sequence spaces described as the domain of this matrix in the space of $p$-summable sequences for $1\leq p \leq \infty$.
Sezer Erdem, Serkan Demiriz
doaj +1 more source
Constitutive modelling of fibre reinforced nonhomogenous hyperelastic materials
MATEC Web of Conferences, 2017 In the paper two classes of poly-convex stored energy functions for transversally isotropic hyper-elastic materials have been proposed. Within these classes, a simplified model of hyper-elastic materials with an isotropic matrix reinforced with fibre ...
Jemioło Stanisław, Gajewski Marcin
doaj +1 more source
Appendix C. Error matrix for vegetation classes from the Gradient Nearest Neighbor structure model.
, 2016 Error matrix for vegetation classes from the Gradient Nearest Neighbor structure ...
Matthew J. Gregory (2904392) +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Hypothetical feature matrix of PSMMs of 4 promoters from two classes and their P values.
, 2016 Hypothetical feature matrix of PSMMs of 4 promoters from two classes and their P values.
Kouser K. (3569339) +3 more
core +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source