Results 101 to 110 of about 3,113,358 (305)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Chern classes for coherent sheaves [PDF]

open access: yes
We present in this paper a construction of Chern classes for a coherent sheaf S on a complex manifold X. In fact we construct classes Cp(S) in H2p(X, C), depending only on the smooth equivalence class of the sheaf S. and analytic classes CAp(S) in Hp(
Green, Howard Ivor
core  

Ridge estimation of covariance matrix from data in two classes

open access: yes
summary:This paper deals with the problem of estimating a covariance matrix from the data in two classes: (1) good data with the covariance matrix of interest and (2) contamination coming from a Gaussian distribution with a different covariance matrix ...
Zhou, Yi, Zhang, Bin
core   +1 more source

On Path Laplacian Eigenvalues and Path Laplacian Energy of Graphs

open access: yesJournal of New Theory, 2018
We introduce the concept of Path Laplacian Matrix for a graph and explore the eigenvalues of this matrix. The eigenvalues of this matrix are called the path Laplacian eigenvalues of the graph.
Shridhar Chandrakant Patekar   +1 more
doaj  

CorrDA: correlation-matrix driven discriminant analysis

open access: yesStatistical Theory and Related Fields
This article introduces a novel approach to integrating correlation matrix information from training samples to construct a classification rule for testing samples.
Feifei Yan   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Grading the Dominant Pathological Indices in Liver Diseases from Pathological Images Using Radiomics Methods

open access: yesFrontiers in Biomedical Technologies
Purpose: This study aims to diagnose the severity of important pathological indices, i.e., fibrosis, steatosis, lobular inflammation, and ballooning from the pathological images of the liver tissue based on extracted features by radiomics methods ...
Hamed Zamanian, Ahmad Shalbaf
doaj   +1 more source

On a class of matrix polynomial equations

open access: yesLinear Algebra and its Applications, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kaashoek, M.A., Lerer, L.
openaire   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy