Results 81 to 90 of about 3,113,358 (305)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A matrix-geometric solution for the multiserver nonpreemptive priority queueing model with mixed priorities. [PDF]
This paper describes the analysis of multiserver queues with nonpreemptive mixed priorities. Such priority structures occur, for example, in initiator settings within the mainframe operating system MVS: job classes have to be assigned to initiators and ...
Leemans, Herlinde, Dedene, Guido
core
On a class of matrix pencils and ℓ-ifications equivalent to a given matrix polynomial
Linear Algebra and its Applications, 2016 20 pages, 8 ...
BINI, DARIO ANDREA, ROBOL, LEONARDO
openaire +2 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
On Spectrum of Some Classes of Matrix Operators
Izvestiya of Saratov University. New Series. Series: Mathematics. Mechanics. Informatics, 2012 Summary: The paper is devoted to investigation of the spectrum of some classes of matrix operators. The relations between the parts of the spectrum of the matrix operators with corresponding parts of its elements are established.
openaire +2 more sources
Streaming Classification with Emerging New Class by Class Matrix Sketching
Proceedings of the AAAI Conference on Artificial Intelligence, 2017 Streaming classification with emerging new class is an important problem of great research challenge and practical value. In many real applications, the task often needs to handle large matrices issues such as textual data in the bag-of-words model and large-scale image analysis.
MU, Xin +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Transition matrix between Leamer classes.
, 2012 For each pair of classes it is measured how often an appearance event of a product from class is observed followed by a disappearance of a product from class , compared to the opposite direction.
Ricardo Hausmann (118136) +2 more
core +1 more source
Generalized notions of amenability for a class of matrix algebras [PDF]
Commentationes Mathematicae Universitatis Carolinae, 2019 We investigate the notions of amenability and its related homological notions for a class of $I\times I$-upper triangular matrix algebra, say $UP(I,A)$, where $A$ is a Banach algebra equipped with a non-zero character. We show that $UP(I,A)$ is pseudo-contractible (amenable) if and only if $I$ is singleton and $A$ is pseudo-contractible (amenable ...
openaire +3 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source