Results 81 to 90 of about 285,460 (269)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

On Path Laplacian Eigenvalues and Path Laplacian Energy of Graphs

Journal of New Theory, 2018
We introduce the concept of Path Laplacian Matrix for a graph and explore the eigenvalues of this matrix. The eigenvalues of this matrix are called the path Laplacian eigenvalues of the graph.
Shridhar Chandrakant Patekar, Maruti Mukinda Shikare   +1 more
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Grading the Dominant Pathological Indices in Liver Diseases from Pathological Images Using Radiomics Methods

Frontiers in Biomedical Technologies
Purpose: This study aims to diagnose the severity of important pathological indices, i.e., fibrosis, steatosis, lobular inflammation, and ballooning from the pathological images of the liver tissue based on extracted features by radiomics methods ...
Hamed Zamanian, Ahmad Shalbaf
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Norms and compactness of operators on absolute weighted mean summable series

Kuwait Journal of Science, 2016
In a recent paper [16], we characterized the classes of triangular matrix transformations mapping the spaces INpI and INqIk into the spaces INqIk and INqI, respectively, where the space INpIk, of series summable by absolute summability method.
Mehmet A. Sarigol
doaj  

Perturbations in the Nevai matrix class of orthogonal matrix polynomials

Linear Algebra and its Applications, 2001
In this paper we study a Jacobi block matrix and the behavior of the limit of its entries when a perturbation of its spectral matrix measure by the addition of a Dirac delta matrix measure is introduced.
Yakhlef, Hossain O., Marcellán, Francisco, Piñar, Miguel A.   +2 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

QUEUEING DISCIPLINES BASED ON PRIORITY MATRIX [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2014
The paper deals with queueing disciplines for demands of general type in queueing systems with multivendor load. A priority matrix is proposed to be used for the purpose of mathematical description of such disciplines, which represents the priority ...
Taufik I. Aliev , Eduards Maharevs
doaj