Results 91 to 100 of about 3,239,599 (306)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A matrix-geometric solution for the multiserver nonpreemptive priority queueing model with mixed priorities. [PDF]

open access: yes
This paper describes the analysis of multiserver queues with nonpreemptive mixed priorities. Such priority structures occur, for example, in initiator settings within the mainframe operating system MVS: job classes have to be assigned to initiators and ...
Leemans, Herlinde, Dedene, Guido
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Symmetry Classes in Random Matrix Theory [PDF]

open access: yes, 2006
Short review article (max. 4000 words) solicited by the editors of the Encylopedia of Mathematical Physics (Elsevier, 2005)
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

On a class of matrix pencils and ℓ-ifications equivalent to a given matrix polynomial

open access: yesLinear Algebra and its Applications, 2016
20 pages, 8 ...
BINI, DARIO ANDREA, ROBOL, LEONARDO
openaire   +2 more sources

The matrix completion problem regarding various classes of P0,1- matrices [PDF]

open access: yes, 2005
A pattern of positions in an n x n real matrix is said to have pi-completion if every partial pi-matrix which specifies that pattern can be completed to a pi-matrix.
Wangsness, Amy
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

On Spectrum of Some Classes of Matrix Operators

open access: yesIzvestiya of Saratov University. New Series. Series: Mathematics. Mechanics. Informatics, 2012
Summary: The paper is devoted to investigation of the spectrum of some classes of matrix operators. The relations between the parts of the spectrum of the matrix operators with corresponding parts of its elements are established.
openaire   +2 more sources

Streaming Classification with Emerging New Class by Class Matrix Sketching

open access: yesProceedings of the AAAI Conference on Artificial Intelligence, 2017
Streaming classification with emerging new class is an important problem of great research challenge and practical value. In many real applications, the task often needs to handle large matrices issues such as textual data in the bag-of-words model and large-scale image analysis.
MU, Xin   +4 more
openaire   +2 more sources

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