Results 51 to 60 of about 1,773,588 (298)

A Simple Space Vector Modulation of High-Frequency AC Linked Three-Phase-to-Single-Phase/DC Converter

IEEE Access, 2020
High frequency (HF) ac linked converter functions well to interface between buses with different voltage types. Using a three-phase-to-single-phase matrix converter, a single-phase cyclo converter, and a HF transformer, we can compose a HF ac linked ...
Yushan Liu, Jie He, Baoming Ge, Xiao Li, Yaosuo Xue, Frede Blaabjerg   +5 more
doaj   +1 more source

Analysis and Design of Three-Phase LLC Resonant Converter with Matrix Transformers

Energies, 2022
This study presents the topology of a three-phase LLC resonant converter with matrix transformers. The three-phase LLC resonant converter has the advantages of conventional LLC resonant converters, including zero-voltage switching at the primary side ...
Jing-Yuan Lin, Hsuan-Yu Yueh, Yi-Feng Lin, Pin-Hsien Liu   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Two-Phase Two-Stage HF Matrix Converter for Supplying Two-Phase Motor Load

, 2013
This paper deals with the two-stage two-phase electronic systems with orthogonal output voltages and currents - DC/HF_AC/2AC. It also introduces the design and prototype of two-stage DC/HF_AC/2AC high frequency converter with two-phase orthogonal output ...
Michal Prazenica, Michal Kabasta, Jozef Buday, Slavomir Kascak, Juraj Koscelnik   +4 more
core   +1 more source

Direct Matrix Converter Topologies with Model Predictive Current Control Applied as Power Interfaces in AC, DC, and Hybrid Microgrids in Islanded and Grid-Connected Modes

Energies, 2019
This paper presents an analysis of a new application of different direct matrix converter topologies used as power interfaces in AC, DC, and hybrid microgrids, with model predictive current control.
Gustavo Gontijo, Matheus Soares, Thiago Tricarico, Robson Dias, Mauricio Aredes, Josep Guerrero   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A SiC-based matrix converter topology for inductive power transfer system

, 2014
Typical inductive power transfer (IPT) systems employ two power conversion stages to generate a high-frequency primary current from low-frequency utility supply.
Vilathgamuwa, D. Mahinda, Madawala, Udaya K., Nguyen, Xuan Bac   +2 more
core   +1 more source

A matrix converter based Inductive Power Transfer system [PDF]

, 2012
Typical Inductive Power Transfer (IPT) systems employ two power conversion stages to generate a high frequency current from low frequency utility supply.
Vilathgamuwa, D. Mahinda, Madawala, Udaya K., Nguyen Xuan Bac, D. Mahinda Vilathgamuwa, Bac, Nguyen Xuan, Udaya K. Madawala   +5 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source