Results 51 to 60 of about 2,032,866 (296)

Mitigation of Complex Non-Linear Dynamic Effects in Multiple Output Cascaded DC-DC Converters

IEEE Access, 2021
In the modern world of technology, the cascaded DC-DC converters with multiple output configurations are contributing a dominant part in the DC distribution systems and DC micro-grids.
Sajjad Ahmed, Syed Abdul Rahman Kashif, Noor Ul Ain, Akhtar Rasool, Muhammad Sohaib Shahid, Sanjeevikumar Padmanaban, Emre Ozsoy, Muhammad Asghar Saqib   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Gradient System Modelling of Matrix Converters with Input and Output Filters [PDF]

, 2003
Due to its complexity, the dynamics of matrix converters are usually neglected in controller design. However, increasing demands on reduced harmonic generation and higher bandwidths makes it necessary to study large-signal dynamics. A unified methodology
Jeltsema, Dimitri, Scherpen, Jacquelien M.A., Klaassens, J. Ben   +2 more
core   +4 more sources

Generating Arbitrary Order Cylindrical Vector Beams With Inherent Transform Mechanism

IEEE Photonics Journal, 2017
Polarization converters that convert incident linearly polarized beams into arbitrary order cylindrical vector beams (CVBs) are derived with the Jones matrix theory.
Xiaoyu Weng, Luping Du, Aiping Yang, Changjun Min, Xiaocong Yuan   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Improving Efficiency of Hybrid Electric Vehicle Using Matrix Converters

Elektronika ir Elektrotechnika, 2019
The paper deals with a novel enhanced connection of AC/AC powertrain for HEV hybrid vehicles. The substantial contribution of such a connection is the absence of 4QC auxiliary converter needed for autonomous and hybrid operational modes and its ...
Branislav Dobrucky, Slavomir Kascak, Michal Prazenica, Miriam Jarabicova   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Open circuit fault detection and diagnosis in matrix converters [PDF]

, 2014
With the increased use of power electronics in aerospace, automotive, industrial, and energy generation sectors, the demand for highly reliable and power dense solutions has increased.
Brunson, C., Empringham, Lee, De Lillo, Liliana, Wheeler, Patrick, Clare, Jon C.   +4 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source